Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.52 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15061432 | 0.82 | CYP19A1 (0.57) | CYP19A1STSCA2CA9 | |
| SCHEMBL5447488 | 0.82 | AR (0.53) | CYP19A1STSCA12CA2CA9 | |
| SCHEMBL5439068 | 0.73 | CYP19A1 (0.73) | CYP19A1STS | |
| SCHEMBL5439425 | 0.73 | CYP19A1 (0.73) | CYP19A1STS | |
| SCHEMBL5441208 | 0.72 | CYP19A1 (0.50) | CYP19A1STS | |
| SCHEMBL5449205 | 0.70 | CYP19A1 (0.50) | CYP19A1 | |
| SCHEMBL5442092 | 0.70 | CYP19A1 (0.75) | CYP19A1STS | |
| SCHEMBL5993003 | 0.69 | CYP19A1 (0.57) | CYP19A1STS | |
| SCHEMBL5445770 | 0.69 | CYP19A1 (0.59) | CYP19A1STS | |
| SCHEMBL5443716 | 0.68 | CA1 (0.58) | CYP19A1STSCA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1890221-B | 1-N-phenyl-amino-1H-imidazole derivatives and pharmaceutical compositions containing them | THERAMEX | 2014-07-16 | — | — | CN | disclosed |
| US-8476455-B2 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | LABORATOIRE THERAMEX (MC) | 2013-07-02 | — | — | US | disclosed |
| US-20070112009-A1 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | LABORATOIRE THERAMEX (MC) | 2007-05-17 | — | — | US | disclosed |
| CN-1890221-A | 1-N-phenyl-amino-1H-imidazole derivatives and pharmaceutical compositions containing them | THERAMEX (MC) | 2007-01-03 | — | — | CN | disclosed |
| EP-1694650-A1 | 1-N-PHENYL-AMINO-1H-IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRE THERAMEX (MC) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005058842-A1 | 1-N-PHENYL-AMINO-1H-IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRE THERAMEX (MC) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112009-A1 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | H1-0, H1-5, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | CYP19A1 761/4885STS 4396/4885CA12 4734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.