SCHEMBL5439477

SCHEMBL5439477

OCCCCCCCC=S

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.40
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.38
GPR84 Q9NQS5 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6884329 1.00 MIF (0.40) MIFLMNAALDH1A1HSD17B10MEN1
SCHEMBL6885113 1.00 MIF (0.40) MIFLMNAALDH1A1HSD17B10MEN1
SCHEMBL6244715 1.00 MIF (0.40) MIFLMNAALDH1A1HSD17B10MEN1
SCHEMBL6885104 1.00 MIF (0.40) MIFLMNAALDH1A1HSD17B10MEN1
SCHEMBL3608167 1.00
SCHEMBL6889171 1.00 MIF (0.40) MIFLMNAALDH1A1HSD17B10MEN1
SCHEMBL8131043 1.00 MIF (0.40) MIFLMNAALDH1A1HSD17B10MEN1
SCHEMBL8098664 1.00 MIF (0.40) MIFLMNAALDH1A1HSD17B10MEN1
SCHEMBL3793874 0.97
SCHEMBL584748 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116375685-B Fasudil derivative and preparation method and application thereof 沈阳药科大学 2023-12-12 CN disclosed
CN-116375685-A Fasudil derivative and preparation method and application thereof 沈阳药科大学 2023-07-04 CN disclosed
US-20070267324-A1 Process and Catalysts for the Production of Linear Alkanes POLIMERI EUROPA S. P. A. (IT) 2007-11-22 US disclosed
WO-2004008550-A2 RAPID LOW-TEMPERATURE SYNTHESIS OF QUANTUM DOTS ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) 2004-01-22 WO disclosed
EP-0850987-B1 Improved PVC foam compositions MORTON INT INC (US) 2002-03-27 EP disclosed
US-5786399-A PVC foam compositions MORTON INTERNATIONAL, INC. (US) 1998-07-28 US disclosed
EP-0850987-A1 Improved PVC foam compositions MORTON INTERNATIONAL, INC. (US) 1998-07-01 EP disclosed
US-5753719-A ACTIVATOR FOR BLOWING AGENTS MORTON INTERNATIONAL, INC. (US) 1998-05-19 US disclosed
US-5726213-A FOAMING VINYL CHLORIDE POLYMER BY HEATING MIXTURE OF POLYMER, BLOWING AGENT, STABILIZER INCLUDING ORGANOTIN MERCAPTIDE OF MERCAPTOALKYL CARBOXYLATE OR SULFIDE THEREOF, OPTIONAL ORGANOTIN SALT MORTON INTERNATIONAL, INC. (US) 1998-03-10 US disclosed
EP-0011456-B1 ORGANOTIN COMPOUNDS AND RESINS OR POLYMERS STABILIZED THEREWITH M & T CHEMICALS, INC. (US) 1983-09-07 EP disclosed
US-RE30810-E HEAT STABILIZERS FOR POLYMERS THIOKOL CORPORATION (US) 1981-12-01 US disclosed
US-4254017-A HEAT STABILIZER FOR POLYVINYL CHLORIDE M&T CHEMICALS INC. (US) 1981-03-03 US disclosed
EP-0011456-A1 Organotin compounds and resins or polymers stabilized therewith M & T CHEMICALS, INC. (US) 1980-05-28 EP disclosed
US-4179432-A 2-HYDROXYBENZOPHENONE, ORGANOTIN MERCAPTIDE PHOTOSTABILITY CINCINNATI MILACRON CHEMICALS, INC. (US) 1979-12-18 US disclosed
US-RE30032-E POLYMER STABILIZERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1979-06-12 US disclosed
US-4120845-A FOR VINYL OR VINYLIDENE HALIDE POLYMERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1978-10-17 US disclosed
US-4062881-A POLYVINYL CHLORIDE CINCINNATI MILACRON CHEMICALS, INC. (US) 1977-12-13 US disclosed
US-3979359-A STABILIZERS FOR VINYL- AND VINYLIDENE HALIDE POLYMERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1976-09-07 US disclosed