Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.82 |
| ▸ | MEN1 | O00255 | 5/20 | 0.82 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.82 |
| ▸ | PDE4A | P27815 | 1/20 | 0.82 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.82 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.82 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5431967 | 1.00 | KMT2A (0.82) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL5426502 | 0.94 | MEN1 (0.84) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL3242127 | 0.94 | MEN1 (0.84) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL3236700 | 0.94 | MEN1 (0.84) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL3242116 | 0.94 | MEN1 (0.84) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL4307435 | 0.94 | MEN1 (0.84) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL13293822 | 0.94 | MEN1 (0.84) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL13293821 | 0.94 | MEN1 (0.84) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL3244539 | 0.94 | MEN1 (0.84) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL7432334 | 0.93 | MEN1 (0.70) | KMT2AMEN1CHRM1PDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070161628-A1 | Phosphodiesterase inhibitors | GREENPHARMA (FR) | 2007-07-12 | — | — | US | claimed |
| US-20070161628-A1 | Phosphodiesterase inhibitors | GREENPHARMA (FR) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161628-A1 | Phosphodiesterase inhibitors | PDE5A, PDE3A, PDE3B | KMT2A 2209/4885MEN1 3432/4885CHRM1 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.