Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAN2B1 | O00754 | 3/20 | 0.39 |
| ▸ | MAN2A1 | Q16706 | 3/20 | 0.39 |
| ▸ | MAN1B1 | Q9UKM7 | 3/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5439352 | 1.00 | EPHX2 (0.44) | EPHX2CCR3RIPK1ALDH1A1LMNA | |
| SCHEMBL3357678 | 0.81 | CYP3A4 (0.50) | EPHX2ALDH1A1LMNA | |
| SCHEMBL3357314 | 0.81 | CYP3A4 (0.50) | EPHX2ALDH1A1LMNA | |
| SCHEMBL3354867 | 0.81 | CYP3A4 (0.50) | EPHX2ALDH1A1LMNA | |
| SCHEMBL21490939 | 0.78 | EPHX2 (0.48) | EPHX2CCR3RIPK1MAN2B1MAN2A1 | |
| SCHEMBL21490940 | 0.78 | EPHX2 (0.48) | EPHX2CCR3RIPK1MAN2B1MAN2A1 | |
| SCHEMBL258306 | 0.77 | MAN2A1 (0.49) | EPHX2CCR3RIPK1ALDH1A1LMNA | |
| Toluene SCHEMBL3905036 | 0.76 | SCN8A (0.46) | EPHX2ALDH1A1LMNA | |
| Toluene SCHEMBL3903571 | 0.76 | SCN8A (0.46) | EPHX2ALDH1A1LMNA | |
| Toluene SCHEMBL3915331 | 0.76 | SCN8A (0.46) | EPHX2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213407-A1 | Compounds to treat Alzheimer's disease | ELAN PHARMACEUTICALS AND PHARMACIA & UPJOHN COMPANY LLC | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213407-A1 | Compounds to treat Alzheimer's disease | PSEN2, PSEN1, CHAT | EPHX2 636/4885CCR3 4057/4885RIPK1 4835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.