Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | TLR4 | O00206 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.55 |
| ▸ | CPB1 | P15086 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5442669 | 1.00 | EPHX1 (0.68) | EPHX1ALDH1A1GAATSHRTLR4 | |
| SCHEMBL5442663 | 1.00 | EPHX1 (0.68) | EPHX1ALDH1A1GAATSHRTLR4 | |
| SCHEMBL29492533 | 1.00 | EPHX1 (0.68) | EPHX1ALDH1A1GAATSHRTLR4 | |
| SCHEMBL28879466 | 0.96 | EPHX1 (0.64) | EPHX1ALDH1A1GAATSHRTLR4 | |
| SCHEMBL10007474 | 0.94 | EPHX1 (0.62) | EPHX1ALDH1A1GAATSHRTLR4 | |
| Cyclobutylcarbamic Acid Benzyl Ester SCHEMBL332814 | 0.94 | EPHX1 (0.76) | EPHX1ALDH1A1GAATSHRTLR4 | |
| SCHEMBL16665079 | 0.93 | EPHX1 (0.61) | EPHX1ALDH1A1GAATSHRTLR4 | |
| SCHEMBL26346079 | 0.93 | EPHX1 (0.61) | EPHX1ALDH1A1GAATSHRTLR4 | |
| SCHEMBL17207590 | 0.93 | EPHX1 (0.61) | EPHX1ALDH1A1GAATSHRTLR4 | |
| Cyclobutylcarbamic Acid Benzyl Ester SCHEMBL579215 | 0.92 | EPHX1 (0.74) | EPHX1ALDH1A1GAATSHRTLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185079-A1 | Therapeutic agents I | ASTRAZENECA AB (SE) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185079-A1 | Therapeutic agents I | HTT, GRIN2A, GRIN1 | EPHX1 568/4885ALDH1A1 1661/4885GAA 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.