⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL45 | 0.82 | — | — | |
| Ethane SCHEMBL119366 | 0.82 | — | — | |
| Ethane SCHEMBL11665218 | 0.82 | — | — | |
| Ethane SCHEMBL11324909 | 0.82 | — | — | |
| Ethane SCHEMBL23673679 | 0.67 | — | — | |
| Ethane SCHEMBL10904760 | 0.67 | — | — | |
| Ethane SCHEMBL55155 | 0.67 | — | — | |
| Ethane SCHEMBL15258695 | 0.67 | — | — | |
| Ethane SCHEMBL9146436 | 0.67 | — | — | |
| Ethane SCHEMBL2959797 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110002877-A1 | PTEN Inhibitors Treat Neutropenia-Associated Pneumonia | CHILDREN'S MEDICAL CENTER CORPORATION | 2011-01-06 | — | — | US | claimed |
| US-11992469-B2 | Targeting mitochondrial dynamics by mitochondrial fusion promoter M1 as a treatment strategy for nervous system injury | CITY UNIVERSITY OF HONG KONG (CN) | 2024-05-28 | — | — | US | disclosed |
| US-20220087957-A1 | Targeting mitochondrial dynamics by mitochondrial fusion promoter M1 as a treatment strategy for nervous system injury | CITY UNIVERSITY OF HONG KONG (CN) | 2022-03-24 | — | — | US | disclosed |
| US-10941194-B2 | Methods of diagnosing and treating autism spectrum disorders | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-03-09 | — | — | US | disclosed |
| US-20190022084-A1 | PROMOTING AXON RENEGERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2019-01-24 | — | — | US | disclosed |
| US-10117866-B2 | Promoting axon regeneration in the adult CNS through control of protein translation | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2018-11-06 | — | — | US | disclosed |
| US-20180002410-A1 | METHODS OF DIAGNOSING AND TREATING AUTISM SPECTRUM DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-01-04 | — | — | US | disclosed |
| US-9492408-B2 | Protection from chemical-induced acute lung injury | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2016-11-15 | — | — | US | disclosed |
| WO-2016118924-A1 | METHODS OF DIAGNOSING AND TREATING AUTISM SPECTRUM DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-07-28 | — | — | WO | disclosed |
| EP-2502623-B1 | Promoting Axon Regeneration in the Adult CNS through Control of Protein Translation | CHILDRENS MEDICAL CENTER (US) | 2016-04-06 | — | — | EP | disclosed |
| US-8367352-B2 | Promoting axon regeneration in the adult CNS through control of protein translation | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2013-02-05 | — | — | US | disclosed |
| EP-2502623-A1 | Promoting Axon Regeneration in the Adult CNS through Control of Protein Translation | Children's Medical Center Corporation (US) | 2012-09-26 | — | — | EP | disclosed |
| US-8110551-B2 | Cytolethal distending toxin and use thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-02-07 | — | — | US | disclosed |
| EP-2282738-A2 | PROMOTING AXON REGENERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | Children's Medical Center Corporation (US) | 2011-02-16 | — | — | EP | disclosed |
| US-20110002877-A1 | PTEN Inhibitors Treat Neutropenia-Associated Pneumonia | CHILDREN'S MEDICAL CENTER CORPORATION | 2011-01-06 | — | — | US | disclosed |
| US-20100068690-A1 | TISSUE PRESERVATION AND FIXATION METHOD | GEORGE MASON INTELLECTUAL PROPERTIES, INC. (US) | 2010-03-18 | — | — | US | disclosed |
| US-20090305333-A1 | Promoting Axon Regeneration in the Adult CNS through Control of Protein Translation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-12-10 | — | — | US | disclosed |
| WO-2009149435-A2 | PROMOTING AXON REGENERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |
| US-20090202592-A1 | CYTOLETHAL DISTENDING TOXIN, INHIBITION AND USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-08-13 | — | — | US | disclosed |
| US-20070203098-A1 | Pten Inhibitors | SEMAFORE PHARMACEUTICALS, INC. (US) | 2007-08-30 | — | — | US | disclosed |