SCHEMBL5445779

SCHEMBL5445779

CCCCCCCCCCCCCCCCCCNC(=S)Nc1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.75
GAA P10253 5/20 0.67
ALDH1A1 P00352 4/20 0.67
EPHX1 P07099 3/20 0.67
HTT P42858 3/20 0.67
MAPT P10636 3/20 0.67
ALOX12 P18054 2/20 0.67
NPSR1 Q6W5P4 1/20 0.67
LMNA P02545 4/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
RAB9A P51151 2/20 0.58
NPC1 O15118 1/20 0.58
MAOA P21397 1/20 0.58
MAOB P27338 1/20 0.58
MEN1 O00255 1/20 0.57
HPGD P15428 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
POLB P06746 1/20 0.56
APOBEC3G Q9HC16 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11068116 1.00 KMT2A (0.75) KMT2AGAAALDH1A1EPHX1HTT
SCHEMBL5445981 1.00 KMT2A (0.75) KMT2AGAAALDH1A1EPHX1HTT
SCHEMBL28223385 1.00 KMT2A (0.75) KMT2AGAAALDH1A1EPHX1HTT
SCHEMBL5447975 1.00 KMT2A (0.75) KMT2AGAAALDH1A1EPHX1HTT
SCHEMBL10667599 1.00 KMT2A (0.75) KMT2AGAAALDH1A1EPHX1HTT
SCHEMBL5446742 1.00 KMT2A (0.75) KMT2AGAAALDH1A1EPHX1HTT
SCHEMBL11438307 0.98 KMT2A (0.77) KMT2AGAAALDH1A1EPHX1HTT
SCHEMBL3958934 0.93 KMT2A (0.80) KMT2AGAAALDH1A1HTTMAPT
SCHEMBL22598038 0.91 KMT2A (0.63) KMT2AGAAALDH1A1EPHX1HTT
SCHEMBL22598037 0.91 KMT2A (0.63) KMT2AGAAALDH1A1EPHX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4421344-A THIOUREA, AND ZINC OXIDE OR HYDROXIDE TO PREVENT FADING OJI PAPER CO., LTD. (JP) 1983-12-20 US claimed
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN disclosed
CN-101129295-A 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems HERAEUS KULZER GMBH (DE) 2008-02-27 CN disclosed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed
EP-0622245-B1 Thermal recording material JUJO PAPER CO LTD (JP) 1998-12-23 EP disclosed
EP-0838345-A1 Thermal recording material NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1998-04-29 EP disclosed
US-5494882-A CONTAINING A DITHIOUREA COMPOUND NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-02-27 US disclosed
EP-0622245-A1 Thermal recording material NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1994-11-02 EP disclosed
US-4421344-A THIOUREA, AND ZINC OXIDE OR HYDROXIDE TO PREVENT FADING OJI PAPER CO., LTD. (JP) 1983-12-20 US disclosed
US-4182690-A WATER TREATMENT OF INSOLBULE POLYOLEFIN, POLYESTER OR POLYAMIDE TEIJIN LIMITED (JP) 1980-01-08 US disclosed
US-4035244-A Electric recording process MITA INDUSTRIAL COMPANY LIMITED (JA) 1977-07-12 US disclosed