Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.81 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.81 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.81 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5740718 | 0.99 | DPP4 (0.83) | DPP4DPP9DPP8FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL5451171 | 0.99 | DPP4 (0.83) | DPP4DPP9DPP8FABP3FABP4 | |
| SCHEMBL5449899 | 0.91 | DPP4 (0.70) | DPP4DPP9DPP8FABP3FABP4 | |
| SCHEMBL5450604 | 0.91 | DPP4 (0.98) | DPP4DPP9DPP8 | |
| Hydrochloric Acid SCHEMBL5455614 | 0.89 | DPP4 (1.00) | DPP4DPP9DPP8 | |
| Hydrochloric Acid SCHEMBL5447311 | 0.89 | DPP4 (0.72) | DPP4DPP9DPP8FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL5740724 | 0.88 | DPP4 (0.66) | DPP4DPP9DPP8 | |
| Cadaverine Tartrate SCHEMBL5451901 | 0.87 | DPP4 (0.85) | DPP4DPP9DPP8 | |
| SCHEMBL5457219 | 0.87 | DPP4 (0.62) | DPP4DPP9DPP8 | |
| Hydrochloric Acid SCHEMBL5443519 | 0.86 | DPP4 (0.82) | DPP4DPP9DPP8FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | US | disclosed |
| EP-1678138-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | Takeda Pharmaceutical Company Limited (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042488-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | DPP4, DPP3, PEPD | DPP4 1/4885DPP9 5/4885DPP8 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.