Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 9/20 | 0.39 |
| ▸ | RAF1 | P04049 | 6/20 | 0.37 |
| ▸ | TEK | Q02763 | 6/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.36 |
| ▸ | BRAF | P15056 | 4/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5447181 | 0.89 | RAF1 (0.44) | CSNK1A1CSNK1DKDRRAF1TEK | |
| SCHEMBL5465658 | 0.87 | CSNK1A1 (0.42) | CSNK1A1CSNK1DKDRRAF1TEK | |
| SCHEMBL5466099 | 0.85 | PDE10A (0.49) | CSNK1A1CSNK1DKDRRAF1TEK | |
| SCHEMBL5444103 | 0.84 | CSNK1A1 (0.49) | CSNK1A1CSNK1DKDRRAF1TEK | |
| SCHEMBL5464185 | 0.83 | CSNK1A1 (0.46) | CSNK1A1CSNK1DKDRRAF1TEK | |
| SCHEMBL5449925 | 0.80 | KDR (0.49) | CSNK1A1CSNK1DKDRRAF1TEK | |
| SCHEMBL5459650 | 0.80 | RAF1 (0.43) | CSNK1A1CSNK1DKDRRAF1TEK | |
| SCHEMBL5459667 | 0.78 | SYK (0.44) | CSNK1A1CSNK1DKDRPDE10AKDM4E | |
| SCHEMBL5456254 | 0.74 | RAF1 (0.44) | CSNK1A1CSNK1DKDRRAF1TEK | |
| SCHEMBL5454095 | 0.73 | PDE10A (0.38) | CSNK1A1CSNK1DKDRRAF1TEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021456-A1 | Aminobenzimidazole derivatives | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | US | claimed |
| US-20070021456-A1 | Aminobenzimidazole derivatives | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021456-A1 | Aminobenzimidazole derivatives | TIE1, KDR, FLT1 | CSNK1A1 609/4885CSNK1D 627/4885KDR 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.