Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951711 | 1.00 | HSD17B10 (0.47) | HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4071083 | 0.80 | DAO (0.61) | HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL26671161 | 0.77 | CYP2A6 (0.43) | HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4070484 | 0.76 | HSD17B10 (0.52) | HSD17B10KDM4EALDH1A1SMN1; SMN2GRIA1 | |
| SCHEMBL29951486 | 0.76 | GRIA1 (0.44) | HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL20798358 | 0.75 | GRIA1 (0.38) | HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL17603345 | 0.73 | GRIA1 (0.42) | HSD17B10KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL19448889 | 0.71 | DAO (0.60) | HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23149455 | 0.71 | GRIA1 (0.35) | KDM4EALDH1A1TSHRGRIA1GRIA2 | |
| SCHEMBL20798344 | 0.71 | GRIA1 (0.35) | HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | ABCG2, ATP5ME, ATP5MG | HSD17B10 1580/4885KDM4E 2403/4885ALDH1A1 1055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.