SCHEMBL5449337

SCHEMBL5449337

C=CCCCC=CCOCCCCCC

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
ALDH1A1 P00352 1/20 0.45
PLA2G2C Q5R387 1/20 0.41
LPAR1 Q92633 1/20 0.41
LPAR2 Q9HBW0 1/20 0.41
LPAR3 Q9UBY5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9785959 1.00 TSHR (0.52) TSHRALDH1A1PLA2G2CLPAR1LPAR2
SCHEMBL5434048 0.98 TSHR (0.48) TSHRALDH1A1PLA2G2CLPAR1LPAR2
SCHEMBL7575927 0.98 TSHR (0.48) TSHRALDH1A1PLA2G2CLPAR1LPAR2
SCHEMBL2861887 0.93 TSHR (0.48) TSHRALDH1A1PLA2G2C
SCHEMBL2861884 0.93 TSHR (0.48) TSHRALDH1A1PLA2G2C
SCHEMBL876481 0.87 TSHR (0.44) TSHRALDH1A1LPAR3
SCHEMBL876483 0.87 TSHR (0.44) TSHRALDH1A1LPAR3
SCHEMBL27445901 0.87 LPAR1 (0.52) LPAR1LPAR2LPAR3
SCHEMBL26753904 0.87 LPAR1 (0.52) LPAR1LPAR2LPAR3
SCHEMBL3204785 0.85 TSHR (0.50) TSHRLPAR1LPAR2LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070027058-A1 Process for producing detergent molecules comprising an ether linkage from butadiene EDWARDS CHARLES L 2007-02-01 US disclosed
US-20070021318-A1 Process for producing detergent molecules comprising an ether linkage from butadiene EDWARDS CHARLES L 2007-01-25 US disclosed
US-7141539-B2 Process for producing detergent molecules comprising an ether linkage from butadiene SHELL OIL COMPANY (US) 2006-11-28 US disclosed
WO-2005019138-A2 PROCESS FOR PRODUCING DETERGENT MOLECULES COMPRISING AN ETHER LINKAGE FROM BUTADIENE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2005-03-03 WO disclosed
US-20050037940-A1 Process for producing detergent molecules comprising an ether linkage from butadiene SHELL OIL COMPANY 2005-02-17 US disclosed