Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98295 | 0.89 | KMT2A (0.43) | MEN1KMT2AHPGDGAAALDH1A1 | |
| SCHEMBL97945 | 0.82 | NPC1 (0.42) | SCN1ASCN5ASCN9ANPC1MAPK13 | |
| SCHEMBL98519 | 0.66 | CHRM1 (0.37) | DRD2DRD4DRD3KCNH2 | |
| SCHEMBL15463880 | 0.65 | NPC1 (0.46) | SCN1ASCN5ASCN9ANPC1MAPK13 | |
| SCHEMBL3054126 | 0.64 | HPGD (0.57) | MEN1KMT2AHPGDALDH1A1EPHX2 | |
| SCHEMBL97167 | 0.64 | KMT2A (0.47) | MEN1KMT2AHPGDGAAALDH1A1 | |
| SCHEMBL97439 | 0.63 | POLB (0.42) | MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL22312379 | 0.63 | SCN1A (0.44) | SCN1ASCN5ASCN9ANPC1MAPK13 | |
| SCHEMBL9687967 | 0.62 | CREBBP (0.39) | SCN1ASCN5ASCN9ANPC1MAPK13 | |
| SCHEMBL11423350 | 0.61 | MEN1 (0.50) | MEN1KMT2AHPGDUSP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |