⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3102539 | 0.74 | — | — | |
| SCHEMBL24649639 | 0.74 | — | — | |
| SCHEMBL3110492 | 0.74 | — | — | |
| SCHEMBL3061566 | 0.73 | — | — | |
| SCHEMBL5802614 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL1336055 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL20526534 | 0.72 | — | — | |
| SCHEMBL31703968 | 0.72 | USP2 (0.52) | — | |
| SCHEMBL21721708 | 0.70 | — | — | |
| SCHEMBL22926478 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104844514-B | Diaryl pyrazole azole compound and preparation method and application | 山东大学 | 2017-11-10 | — | — | CN | claimed |
| CN-114668761-A | Novel ferroportin inhibitors | 威佛（国际）股份公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-108290878-B | Novel ferroportin inhibitors | 威佛（国际）股份公司 | 2022-04-26 | — | — | CN | disclosed |
| US-11066399-B2 | Ferroportin inhibitors | VIFOR (INTERNATIONAL) AG (CH) | 2021-07-20 | — | — | US | disclosed |
| US-20210139472-A1 | Novel Ferroportin Inhibitors | VIFOR (INTERNATIONAL) AG (CH) | 2021-05-13 | — | — | US | disclosed |
| US-11001579-B2 | Ferroportin inhibitors | VIFOR (INTERNATIONAL) AG (CH) | 2021-05-11 | — | — | US | disclosed |
| US-10738041-B2 | Ferroportin inhibitors | VIFOR (INTERNATIONAL) AG (CH) | 2020-08-11 | — | — | US | disclosed |
| US-20190345151-A1 | Novel Ferroportin Inhibitors | VIFOR (INTERNATIONAL) AG (CH) | 2019-11-14 | — | — | US | disclosed |
| US-10364239-B2 | Ferroportin inhibitors | VIFOR (INTERNATIONAL) AG (CH) | 2019-07-30 | — | — | US | disclosed |
| CN-108774214-A | Heterocyclic amides as kinase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-11-09 | — | — | CN | disclosed |
| WO-2017068090-A1 | NOVEL FERROPORTIN INHIBITORS | VIFOR (INTERNATIONAL) AG (CH) | 2017-04-27 | — | — | WO | disclosed |
| CN-106573936-A | 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one compounds and their use as negative allosteric modulators of mglur2 receptors | 詹森药业有限公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-104557860-B | A kind of adjacent formamido heterocyclic carbamate derivatives, its preparation method and a kind of insecticide | 浙江新安化工集团股份有限公司 | 2017-03-15 | — | — | CN | disclosed |
| CN-102432639-B | 1-(2-hydroxy-3-(phenylamino)propyl)-3-ferrocenyl-1H-pyrazole-5-ethyl formate compound and medicinal use thereof | UNIV SHANDONG | 2013-11-06 | — | — | CN | disclosed |
| CN-102015679-A | 1-substituted pyridyl-pyrazole amide compound and application thereof | SINOCHEM CORP | 2011-04-13 | — | — | CN | disclosed |
| CN-100577658-C | Quinazoline derivatives | ASTRAZENECA AB | 2010-01-06 | — | — | CN | disclosed |
| US-20070043010-A1 | Quinazoline derivatives | ASTRAZENECA UK LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
| CN-1886399-A | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2006-12-27 | — | — | CN | disclosed |
| EP-1670786-A1 | QUINAZOLINE DERIVATIVES | Astrazeneca AB (SE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030757-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-04-07 | — | — | WO | disclosed |