Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 3/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 5/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694605 | 1.00 | PDE4B (0.51) | PDE4BMEN1KMT2ATACR1SCN9A | |
| SCHEMBL12602246 | 1.00 | PDE4B (0.51) | PDE4BMEN1KMT2ATACR1SCN9A | |
| SCHEMBL15144418 | 1.00 | PDE4B (0.51) | PDE4BMEN1KMT2ATACR1SCN9A | |
| SCHEMBL6694614 | 1.00 | PDE4B (0.51) | PDE4BMEN1KMT2ATACR1SCN9A | |
| SCHEMBL951033 | 1.00 | PDE4B (0.51) | PDE4BMEN1KMT2ATACR1SCN9A | |
| SCHEMBL3065548 | 1.00 | PDE4B (0.51) | PDE4BMEN1KMT2ATACR1SCN9A | |
| SCHEMBL3054630 | 0.91 | MEN1 (0.44) | PDE4BMEN1KMT2ATACR1SCN9A | |
| SCHEMBL14934670 | 0.91 | PDE4B (0.51) | PDE4BMEN1KMT2ATACR1HDAC1 | |
| SCHEMBL3008782 | 0.91 | PDE4B (0.51) | PDE4BMEN1KMT2ATACR1HDAC1 | |
| SCHEMBL18780248 | 0.91 | PDE4B (0.51) | PDE4BMEN1KMT2ATACR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142389-A1 | PIPERIDINE DERIVATIVES | PFIZER INC. (US) | 2007-06-21 | — | — | US | disclosed |
| EP-1384711-A1 | Optical resolution of a piperidine derivative | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2004-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142389-A1 | PIPERIDINE DERIVATIVES | CFTR, HDAC10, RPP30 | PDE4B 975/4885MEN1 1455/4885KMT2A 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.