Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5447358 | 0.91 | TEK (0.30) | TEK | |
| SCHEMBL5458910 | 0.85 | — | — | |
| SCHEMBL5448421 | 0.85 | TEK (0.37) | TEKKDR | |
| SCHEMBL5459692 | 0.81 | KDR (0.31) | KDR | |
| SCHEMBL5452236 | 0.76 | KDR (0.37) | TEKKDR | |
| SCHEMBL5449919 | 0.76 | KDR (0.36) | TEKKDR | |
| SCHEMBL5444068 | 0.76 | TEK (0.37) | TEKKDR | |
| SCHEMBL5452397 | 0.72 | PIM1 (0.31) | KDR | |
| SCHEMBL5447170 | 0.71 | RAF1 (0.33) | TEKKDR | |
| SCHEMBL5899309 | 0.71 | RAF1 (0.53) | TEKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021456-A1 | Aminobenzimidazole derivatives | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | US | claimed |
| EP-1656377-A1 | AMINOBENZIMIDAZOLE DERIVATIVES | MERCK PATENT GmbH (DE) | 2006-05-17 | — | — | EP | claimed |
| WO-2005019216-A1 | AMINOBENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-03-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021456-A1 | Aminobenzimidazole derivatives | TIE1, KDR, FLT1 | TEK 4/4885KDR 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.