SCHEMBL5452732

SCHEMBL5452732

C=CC[SiH2]C(OC(C)=O)OC(C)=O

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
MAPT P10636 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
GALR3 O60755 1/20 0.31
BLM P54132 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
USP2 O75604 1/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6902874 0.81
SCHEMBL703726 0.75 TSHR (0.43) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL705828 0.75 TSHR (0.43) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL2284390 0.72 TSHR (0.34) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL2050713 0.71 TSHR (0.40) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL706118 0.71 TSHR (0.40) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL703250 0.71 TSHR (0.40) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL4637295 0.71 TSHR (0.40) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL1780920 0.70
SCHEMBL2290076 0.69 TSHR (0.31) TSHRMAPTSMN1; SMN2TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072128-A1 COLORANT COMPOSITION AND COATED ARTICLE GUANGDONG HUARUN PAINTS CO., LTD. (CN) 2023-05-04 WO claimed
CN-113956727-A Colorant composition and coated article 广东华润涂料有限公司 2022-01-21 CN claimed
US-20070173935-A1 Nucleus pulposus augmentation pretreatment technique DEPUY SPINE, INC. 2007-07-26 US claimed
EP-4737517-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737513-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737515-A1 RUBBER COMPOSITION FOR TIRES, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737516-A1 RUBBER COMPOSITION FOR TIRES, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-3604439-B1 RUBBER COMPOSITION AND CROSSLINKED RUBBER ZEON CORP (JP) 2026-01-14 EP disclosed
EP-4640736-A1 RING-OPENED COPOLYMER, RUBBER COMPOSITION, RUBBER CROSS-LINKED PRODUCT, AND TIRE Zeon Corporation (JP) 2025-10-29 EP disclosed
WO-2025070000-A1 RUBBER COMPOSITION, CROSSLINKED RUBBER, AND TIRE 日本ゼオン株式会社 2025-04-03 WO disclosed
EP-3822317-B1 RING-OPENING COPOLYMER COMPOSITION ZEON CORP (JP) 2025-02-26 EP disclosed
EP-1266766-A1 Transfer sheets Daicel Chemical Industries, Ltd. (JP) 2002-12-18 EP disclosed
US-20020160162-A1 Recording sheets and process for the production thereof DAICEL CHEMICAL INDUSTRIES, LTD. 2002-10-31 US disclosed
US-6465078-B1 POLYETHYLENE TEREPHTHALATE SUBSTRATES HAVING CATIONIC COPOLYMER COATINGS, COUPLERS AND HYROPHILIC POLYMERS, USED FOR INK JET PRINTERS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-10-15 US disclosed
US-6455133-B1 STRETCHED STYRENIC SHEET IS TEARABLE; PARTICULATE LUBRICANT; OVERHEAD PROJECTORS; ABSORPTION DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-09-24 US disclosed
EP-0956971-B1 Ink-receptor sheet for ink-jet printing and method for producing the same DAICEL CHEM (JP) 2002-07-10 EP disclosed
EP-1114734-A1 RESIN COMPOSITION FOR INK-JET RECORDING SHEET AND RECORDING SHEET MADE WITH THE SAME DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2001-07-11 EP disclosed
EP-0989162-A1 THERMOPLASTIC RESIN COMPOSITION, WATER-BASED COMPOSITION, HEAT-SENSITIVE PRESSURE-SENSITIVE ADHESIVE, AND HEAT-SENSITIVE SHEET Daicel Chemical Industries, Ltd. (JP) 2000-03-29 EP disclosed
EP-0956971-A1 Ink-receptor sheet for ink-jet printing and method for producing the same Daicel Chemical Industries, Ltd. (JP) 1999-11-17 EP disclosed
EP-0896883-A1 RECORDING SHEETS AND PROCESS FOR THE PRODUCTION THEREOF DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-02-17 EP disclosed