Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496530 | 0.76 | — | — | |
| SCHEMBL15841436 | 0.74 | TSHR (0.36) | TSHR | |
| SCHEMBL2699105 | 0.71 | TSHR (0.59) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL13419032 | 0.70 | TSHR (0.46) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL9453883 | 0.70 | TSHR (0.46) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL992095 | 0.70 | TSHR (0.46) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL13454198 | 0.70 | TSHR (0.46) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL19333598 | 0.70 | TSHR (0.46) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL3503019 | 0.70 | — | — | |
| SCHEMBL18689521 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173935-A1 | Nucleus pulposus augmentation pretreatment technique | DEPUY SPINE, INC. | 2007-07-26 | — | — | US | claimed |
| US-20070173935-A1 | Nucleus pulposus augmentation pretreatment technique | DEPUY SPINE, INC. | 2007-07-26 | — | — | US | disclosed |