Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 4/20 | 0.72 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452849 | 1.00 | TOP2A (0.72) | TOP2AAKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL31722975 | 0.95 | TOP2A (0.63) | TOP2AAKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL30886669 | 0.95 | TOP2A (0.63) | TOP2AAKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL27214652 | 0.95 | TOP2A (0.63) | TOP2AAKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL27214671 | 0.95 | TOP2A (0.63) | TOP2AAKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL31722977 | 0.93 | TOP2A (0.65) | TOP2AAKR1C3AKR1C2KDM4EALOX15 | |
| SCHEMBL27231190 | 0.93 | TOP2A (0.65) | TOP2AAKR1C3AKR1C2KDM4EALOX15 | |
| SCHEMBL27214654 | 0.93 | TOP2A (0.65) | TOP2AAKR1C3AKR1C2KDM4EALOX15 | |
| SCHEMBL30886656 | 0.93 | TOP2A (0.65) | TOP2AAKR1C3AKR1C2KDM4EALOX15 | |
| SCHEMBL27231191 | 0.93 | TOP2A (0.65) | TOP2AAKR1C3AKR1C2KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070122862-A1 | Screening for lipolytic enzymes or amidase activity | NOVOZYMES A/S (DK) | 2007-05-31 | — | — | US | disclosed |