Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Isobutane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutane SCHEMBL27082101 | 1.00 | CA1 (0.56) | CA1CA2CA9TP53FFAR3 | |
| Isobutane SCHEMBL28694060 | 1.00 | CA1 (0.56) | CA1CA2CA9TP53FFAR3 | |
| Isobutane SCHEMBL28050909 | 1.00 | CA1 (0.56) | CA1CA2CA9TP53FFAR3 | |
| Isobutane SCHEMBL13372605 | 1.00 | CA1 (0.56) | CA1CA2CA9TP53FFAR3 | |
| Isobutane SCHEMBL28410846 | 1.00 | CA1 (0.56) | CA1CA2CA9TP53FFAR3 | |
| Isobutane SCHEMBL1580573 | 1.00 | — | — | |
| Isobutane SCHEMBL132611 | 1.00 | CA1 (0.56) | CA1CA2CA9TP53FFAR3 | |
| Isobutane SCHEMBL6337855 | 1.00 | CA1 (0.56) | CA1CA2CA9TP53FFAR3 | |
| Isobutane SCHEMBL43551 | 1.00 | CA1 (0.56) | CA1CA2CA9TP53FFAR3 | |
| Isobutane SCHEMBL5079904 | 0.95 | TP53 (0.50) | CA1CA2CA9TP53FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 104431 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637702-B2 | Process for preparing substituted imidazo[1,5-α]pyrazines | HOFFMANN-LA ROCHE INC. (US) | 2026-05-26 | — | — | US | claimed |
| CN-122080089-A | Method for synthesizing ferrocene isoquinoline and ferrocene dihydro isoquinoline planar chiral compounds | — | 2026-05-26 | — | — | CN | claimed |
| CN-122079809-A | Synthesis method of dipeptide linker of antibody coupling degradation agent | — | 2026-05-26 | — | — | CN | claimed |
| CN-122079847-A | Key intermediate of 3-hydroxymethyl azetidine-1-carboxylic acid tert-butyl ester and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122070936-A | Nanometer material based on supermolecule polypeptide-drug coupling prodrug, and preparation method and application thereof | 中国医学科学院生物医学工程研究所 | 2026-05-22 | — | — | CN | claimed |
| CN-121471090-B | Photoresist agent based on alkynyl bridging and biphenyl structure, preparation method and application | 南开大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122059936-A | DASA compound and preparation method and application thereof | 中山大学 | 2026-05-19 | — | — | CN | claimed |
| CN-116891461-B | Synthesis method of SERD intermediate | 罗欣药业(上海)有限公司 | 2026-05-15 | — | — | CN | claimed |
| WO-2026099776-A1 | A PROCESS FOR THE PREPARATION OF PACLITAXEL | FRESENIUS KABI ONCOLOGY LTD. (IN) | 2026-05-15 | — | — | WO | claimed |
| CN-116813670-B | Large-steric-hindrance C-C coupled palladium ligand and synthesis method thereof | 西安欧得光电材料有限公司 | 2026-05-15 | — | — | CN | claimed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | claimed |
| WO-1989007103-A1 | PYRANOBENZOXADIAZOLE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-08-10 | — | — | WO | claimed |
| EP-0327127-A1 | Pyranobenzoxadiazole derivatives, preparation, use and compositions comprising them | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-09 | — | — | EP | claimed |
| EP-0309006-A1 | N-substituted-4,9-dioxa-1,12-dodecanediamines useful for preparing nucleic acid intercalators | CETUS CORPORATION (US) | 1989-03-29 | — | — | EP | claimed |
| EP-0274423-A2 | Method for the production of crystalline amino-protected-beta-benzyl-L-aspartic acid | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-07-13 | — | — | EP | claimed |
| EP-0256559-A2 | Process for producing di-tertiary-butyl dicarbonate | MITSUBISHI KASEI CORPORATION (JP) | 1988-02-24 | — | — | EP | claimed |
| US-4713480-A | Method for the production of crystalline amino-protected-beta-benzyl-L-aspartic acid | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-12-15 | — | — | US | claimed |
| US-4672129-A | Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones | WARNER-LAMBERT COMPANY (US) | 1987-06-09 | — | — | US | claimed |
| EP-0210857-A1 | Process for the preparation of alkyl 2-carboalkoxy-3,4-dialkoxybenzenecarbamates | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-02-04 | — | — | EP | claimed |
| US-4617417-A | Alkyl 2-carboalkoxy-3,4-dialkoxybenzenecarbamates and process for their preparation | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-10-14 | — | — | US | claimed |