Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5445074 | 0.89 | DPP4 (0.56) | DPP4DPP8DPP9 | |
| SCHEMBL5450219 | 0.88 | DPP4 (0.50) | DPP4DPP8DPP9GHSR | |
| SCHEMBL5739714 | 0.85 | DPP4 (0.47) | DPP4DPP8DPP9GHSR | |
| Hydrochloric Acid SCHEMBL5441446 | 0.84 | DPP4 (0.61) | DPP4DPP8DPP9 | |
| SCHEMBL5441483 | 0.83 | DPP4 (0.54) | DPP4DPP8DPP9 | |
| SCHEMBL5802632 | 0.83 | DPP4 (0.46) | DPP4DPP8DPP9 | |
| SCHEMBL5441432 | 0.82 | DPP4 (0.49) | DPP4DPP8DPP9 | |
| SCHEMBL4111176 | 0.82 | DPP4 (0.59) | DPP4DPP8DPP9 | |
| SCHEMBL5449864 | 0.81 | DPP4 (0.71) | DPP4DPP8DPP9 | |
| SCHEMBL5801017 | 0.80 | DPP4 (0.67) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | DPP4, DPP3, PEPD | DPP4 1/4885DPP8 8/4885DPP9 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.