Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.69 |
| ▸ | KIT | P10721 | 2/20 | 0.69 |
| ▸ | BRAF | P15056 | 11/20 | 0.66 |
| ▸ | KDR | P35968 | 2/20 | 0.66 |
| ▸ | RAF1 | P04049 | 2/20 | 0.66 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.66 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.66 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.64 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.64 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.64 |
| ▸ | LCK | P06239 | 2/20 | 0.61 |
| ▸ | BTK | Q06187 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | BMX | P51813 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18164577 | 0.81 | MAPK14 (0.75) | CSF1RKITBRAFKDRRAF1 | |
| SCHEMBL22145723 | 0.81 | BRAF (0.67) | CSF1RKITBRAFKDRRAF1 | |
| SCHEMBL18164405 | 0.80 | BMX (0.83) | CSF1RKITBRAFKDRMAPK14 | |
| SCHEMBL16735230 | 0.80 | BRAF (1.00) | CSF1RKITBRAFKDRRAF1 | |
| SCHEMBL22145722 | 0.79 | CSF1R (0.65) | CSF1RKITBRAFKDRRAF1 | |
| SCHEMBL4790008 | 0.79 | BRAF (0.62) | CSF1RKITBRAFKDRRAF1 | |
| SCHEMBL31524168 | 0.79 | BRAF (0.58) | CSF1RKITBRAFKDR | |
| SCHEMBL18181677 | 0.79 | BMX (0.57) | CSF1RKITBRAFMAPK14ABL1 | |
| SCHEMBL18164222 | 0.79 | MAPK14 (0.84) | CSF1RKITBRAFKDRRAF1 | |
| SCHEMBL3806174 | 0.79 | BRAF (0.77) | CSF1RKITBRAFKDRRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259849-A1 | Azine-Carboxamides as Anti-Cancer Agents | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | claimed |
| US-20070259849-A1 | Azine-Carboxamides as Anti-Cancer Agents | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259849-A1 | Azine-Carboxamides as Anti-Cancer Agents | ARAF, BRAF, RAF1 | CSF1R 1016/4885KIT 144/4885BRAF 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.