Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457765 | 0.83 | KDM4E (0.62) | KDM4EALDH1A1LMNAKMT2AHSD17B10 | |
| SCHEMBL4074624 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1LMNAKMT2AHSD17B10 | |
| SCHEMBL4072282 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1LMNAKMT2AHSD17B10 | |
| SCHEMBL4074136 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1LMNAKMT2AHSD17B10 | |
| SCHEMBL4071048 | 0.78 | USP2 (0.53) | KDM4EALDH1A1LMNAKMT2AHSD17B10 | |
| SCHEMBL4077833 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1LMNAKMT2AHSD17B10 | |
| SCHEMBL4081674 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1LMNAKMT2AHSD17B10 | |
| SCHEMBL4074530 | 0.74 | KDM4E (0.56) | KDM4EALDH1A1LMNAKMT2AHSD17B10 | |
| SCHEMBL4074094 | 0.74 | KDM4E (0.61) | KDM4EALDH1A1LMNAKMT2AHSD17B10 | |
| SCHEMBL4071631 | 0.74 | KDM4E (0.70) | KDM4EALDH1A1LMNAKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2007-12-13 | — | — | US | claimed |
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | ABCG2, ATP5ME, ATP5MG | KDM4E 2403/4885ALDH1A1 1055/4885LMNA 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.