SCHEMBL5453760

SCHEMBL5453760

O=C(O)C1C(C(=O)O)C(F)(C(=O)O)C1C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
GRM2 Q14416 3/20 0.31
GRM3 Q14832 3/20 0.31
GRM8 O00222 1/20 0.31
GRM6 O15303 1/20 0.31
ALDH1A1 P00352 3/20 0.31
TP53 P04637 1/20 0.30
ALOX15 P16050 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3480615 0.68 GRM2 (0.45) GRM2GRM3GRM8GRM6
SCHEMBL1286184 0.68 TDP1 (0.35) GRM2GRM3GRM6ALDH1A1TP53
SCHEMBL2855181 0.64 POLB (0.34) KDM4EGRM2GRM3GRM8GRM6
SCHEMBL21380243 0.61
SCHEMBL10949582 0.61 GRM2 (0.32) GRM2GRM3
SCHEMBL638317 0.61
SCHEMBL8025152 0.61
SCHEMBL9782987 0.61 POLB (0.47) KDM4ECYP1A2CYP2D6GRM2GRM3
SCHEMBL9271352 0.61 POLB (0.47) KDM4ECYP1A2CYP2D6GRM2GRM3
SCHEMBL9782996 0.61 POLB (0.47) KDM4ECYP1A2CYP2D6GRM2GRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101153971-B Liquid crystal display SAMSUNG ELECTRONICS CO LTD 2010-12-01 CN claimed
CN-101153971-A Liquid crystal display SAMSUNG ELECTRONICS CO LTD (KR) 2008-04-02 CN claimed
US-20070092743-A1 Liquid crystal display SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-04-26 US claimed
CN-109804306-A Light orientation copolymer material 罗利克技术有限公司 2019-05-24 CN disclosed
CN-108912011-A Light arrangement material 罗立克科技股份公司 2018-11-30 CN disclosed
CN-101153971-B Liquid crystal display SAMSUNG ELECTRONICS CO LTD 2010-12-01 CN disclosed
CN-100430802-C Liquid crystal display device and method for manufacturing the same HITACHI LTD (JP) 2008-11-05 CN disclosed
CN-101153971-A Liquid crystal display SAMSUNG ELECTRONICS CO LTD (KR) 2008-04-02 CN disclosed
US-20070092743-A1 Liquid crystal display SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-04-26 US disclosed
CN-1723413-A Liquid crystal display and method for manufacturing same HITACHI LTD (JP) 2006-01-18 CN disclosed