Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17395798 | 0.96 | BRD4 (0.50) | BRD4CREBBPPKMCA12CA1 | |
| SCHEMBL5451013 | 0.90 | CA12 (0.56) | BRD4CREBBPPKMCA12CA1 | |
| SCHEMBL30694770 | 0.87 | BRD4 (0.45) | BRD4CREBBPPKMCA12CA1 | |
| SCHEMBL25369619 | 0.87 | BRD4 (0.45) | BRD4CREBBPPKMCA12CA1 | |
| SCHEMBL4651610 | 0.87 | CA12 (0.50) | BRD4CREBBPCA12CA1CA2 | |
| SCHEMBL27721005 | 0.85 | TPMT (0.40) | BRD4CREBBPPKMCA12CA1 | |
| SCHEMBL6017515 | 0.84 | UNG (0.43) | BRD4CREBBPPKMCA12CA1 | |
| SCHEMBL4652562 | 0.82 | CYP2C9 (0.55) | BRD4CREBBPCA12CA1CA2 | |
| SCHEMBL23978213 | 0.82 | TP53 (0.47) | TP53SMN1; SMN2POLBTDP1TPMT | |
| SCHEMBL15123387 | 0.82 | BRD4 (0.40) | BRD4CREBBPPKMCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530512-B2 | Broad spectrum gram-positive antimicrobials and anthelmintics with efficacy against drug-resistant strains and Mycobacterium species | MONTE AARON P (US) | 2013-09-10 | — | — | US | disclosed |
| US-20070292545-A1 | ANTI-INFECTIVE AGENTS AND METHODS OF USE | WISYS TECHNOLOGY FOUNDATION | 2007-12-20 | — | — | US | disclosed |
| CN-1319959-C | Hydroxystilbene, stilbene derivatives and analogues thereof for anti-inflammatory treatment of psoriasis and inhibition of protein kinase | CHEN GENHUI (CN) | 2007-06-06 | — | — | CN | disclosed |
| CN-1407978-A | Anti-inflammatory, psoriasis treatment and protein kinase inhibition using hydroxystilbenes, novel stilbene derivatives and analogues thereof | GENHUI CHEN (CA) | 2003-04-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070292545-A1 | ANTI-INFECTIVE AGENTS AND METHODS OF USE | H1-3, H1-0, H1-2 | BRD4 438/4885CREBBP 3175/4885PKM 4657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.