SCHEMBL5457375

SCHEMBL5457375

CCCCCCCc1cc2cn(OCCCCC)c(=O)nc2o1

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.42
ELANE P08246 3/20 0.35
ALOX15 P16050 1/20 0.33
STS P08842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14430913 0.81 MAPT (0.47) MAPTELANEALOX15
SCHEMBL14430889 0.79 MAPT (0.45) MAPTELANEALOX15
SCHEMBL14430887 0.79 MAPT (0.45) MAPTELANEALOX15
SCHEMBL5470194 0.79 MAPT (0.45) MAPTELANEALOX15
SCHEMBL5460983 0.77 MAPT (0.41) MAPTELANE
SCHEMBL14430892 0.77 MAPT (0.41) MAPTELANE
SCHEMBL5468306 0.77 MAPT (0.43) MAPTELANEALOX15
SCHEMBL14430894 0.77 MAPT (0.43) MAPTELANEALOX15
SCHEMBL14430896 0.76 MAPT (0.41) MAPTELANE
SCHEMBL14430898 0.74 NPC1 (0.40) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070191373-A1 Heterocyclic compounds for use in the treatment of viral infections REGAN FOUNDATION (BE) 2007-08-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070191373-A1 Heterocyclic compounds for use in the treatment of viral infections TPMT, TYMP, HAVCR2 MAPT 3202/4885ELANE 1968/4885ALOX15 2560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.