Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 17/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5356088 | 0.88 | PTH1R (0.65) | PTH1R | |
| SCHEMBL5347247 | 0.88 | PTH1R (0.57) | PTH1RCCKBR | |
| SCHEMBL5351792 | 0.87 | PTH1R (0.56) | PTH1RPIK3CA | |
| SCHEMBL5480267 | 0.87 | PTH1R (0.58) | PTH1RCCKBR | |
| SCHEMBL5352872 | 0.87 | PTH1R (0.55) | PTH1RCCKBR | |
| SCHEMBL5364026 | 0.86 | PTH1R (0.54) | PTH1RCES2 | |
| SCHEMBL5348222 | 0.85 | PTH1R (0.54) | PTH1R | |
| SCHEMBL5366388 | 0.85 | PTH1R (0.54) | PTH1R | |
| SCHEMBL5359898 | 0.83 | PTH1R (0.64) | PTH1R | |
| SCHEMBL5355230 | 0.82 | PTH1R (0.68) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135350-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |