Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468341 | 0.91 | TMEM97 (0.63) | ALDH1A1MEN1KMT2AMAPK1HRH3 | |
| SCHEMBL5458190 | 0.90 | HRH3 (0.55) | ALDH1A1MEN1KMT2AMAPK1HRH3 | |
| SCHEMBL5462288 | 0.89 | HRH3 (0.59) | ALDH1A1MEN1KMT2AMAPK1HRH3 | |
| SCHEMBL5472280 | 0.89 | HRH3 (0.59) | ALDH1A1MEN1KMT2AMAPK1HRH3 | |
| SCHEMBL5458846 | 0.89 | HRH3 (0.74) | ALDH1A1MEN1KMT2AHRH3TMEM97 | |
| SCHEMBL5468208 | 0.89 | HRH3 (0.56) | ALDH1A1MEN1KMT2AMAPK1HRH3 | |
| SCHEMBL5468173 | 0.89 | HRH3 (0.59) | ALDH1A1MEN1KMT2AMAPK1HRH3 | |
| SCHEMBL5458924 | 0.87 | HRH3 (0.66) | ALDH1A1MEN1KMT2AMAPK1HRH3 | |
| SCHEMBL5455761 | 0.87 | HRH3 (0.54) | ALDH1A1MEN1KMT2AMAPK1HRH3 | |
| SCHEMBL5464285 | 0.86 | HRH3 (0.56) | ALDH1A1MEN1KMT2AMAPK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | CNR2, GRIN2C, GRIN2B | ALDH1A1 1805/4885MEN1 4497/4885KMT2A 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.