Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.61 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.61 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28230851 | 0.91 | MAPT (0.66) | MAPTSMN1; SMN2BLMCYP2C19CYP3A4 | |
| SCHEMBL28869329 | 0.89 | MAPT (1.00) | MAPTSMN1; SMN2BLMCYP2C19KMT2A | |
| Tert-Butyl Formate SCHEMBL28032936 | 0.89 | MAPT (0.63) | MAPTSMN1; SMN2BLMCYP2C19CYP3A4 | |
| SCHEMBL4559572 | 0.86 | SMN1; SMN2 (0.91) | MAPTSMN1; SMN2BLMCYP2C19CYP3A4 | |
| SCHEMBL8361624 | 0.86 | SMN1; SMN2 (0.97) | MAPTSMN1; SMN2BLMCYP3A4KMT2A | |
| SCHEMBL6716470 | 0.85 | MAPT (0.65) | MAPTSMN1; SMN2BLMCYP2C19CYP3A4 | |
| SCHEMBL5195426 | 0.84 | SMN1; SMN2 (1.00) | MAPTSMN1; SMN2BLMKMT2ACYP2D6 | |
| SCHEMBL13097610 | 0.84 | POLB (0.58) | MAPTSMN1; SMN2BLMCYP2C19CYP3A4 | |
| SCHEMBL27647454 | 0.84 | KMT2A (0.61) | MAPTSMN1; SMN2CYP2C19KMT2APOLB | |
| SCHEMBL3949148 | 0.83 | MAPT (0.88) | MAPTSMN1; SMN2BLMCYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079899-A | Application of pharmaceutical composition in preparation of medicines for preventing or treating diseases related to Sirttail 7 protein | — | 2026-05-26 | — | — | CN | disclosed |
| EP-4678234-A1 | ANTAGONIST HETEROCYCLIC COMPOUNDS INVOLVED IN THE CGAS-STING ROUTE | Centre National de la Recherche Scientifique (FR) | 2026-01-14 | — | — | EP | disclosed |
| CN-116829542-A | Benzothiazole and benzimidazole derivatives, pharmaceutically acceptable salts, preparation method thereof and pharmaceutical composition containing same as active ingredient | 韩国化学研究院 | 2023-09-29 | — | — | CN | disclosed |
| WO-2023144737-A1 | COMPOSITIONS FOR PREVENTING OR TREATING HEART FAILURE (HF) | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144736-A1 | COMPOSITIONS FOR PREVENTING OR TREATING PULMONARY ARTERIAL HYPERTENSION | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-03 | — | — | WO | disclosed |
| EP-3127912-B1 | TRIPEPTIDE EPOXYKETONE COMPOUND CONSTRUCTED BY HETEROCYCLE AND PREPARATION METHOD AND USE THEREOF | UNIV ZHEJIANG (CN) | 2021-04-21 | — | — | EP | disclosed |
| CN-104945470-B | Tripeptide epoxy ketone compound constructed by heterocycle, preparation and application | 浙江大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-108137518-A | As 6 inhibitor of histone deacetylase 1,3,4- oxadiazole derivatives compound and include its pharmaceutical composition | 株式会社钟根堂 | 2018-06-08 | — | — | CN | disclosed |
| US-9856288-B2 | Tripeptide epoxyketone compound constructed by heterocycle and preparation method and use thereof | ZHEJIANG UNIVERSITY (CN) | 2018-01-02 | — | — | US | disclosed |
| EP-3127912-A1 | TRIPEPTIDE EPOXYKETONE COMPOUND CONSTRUCTED BY HETEROCYCLE AND PREPARATION METHOD AND USE THEREOF | Zhejiang University (CN) | 2017-02-08 | — | — | EP | disclosed |
| US-20170022250-A1 | TRIPEPTIDE EPOXYKETONE COMPOUND CONSTRUCTED BY HETEROCYCLE AND PREPARATION METHOD AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA , CHINESE ACADEMY OF SCIENCES (CN) | 2017-01-26 | — | — | US | disclosed |
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | disclosed |
| US-4607034-A | HYPOTENSIVE AGENTS | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-08-19 | — | — | US | disclosed |
| EP-0028031-B1 | NOVEL QUINAZOLINE DERIVATIVES, A PHARMACEUTICAL COMPOSITION CONTAINING SUCH DERIVATIVES AS ACTIVE INGREDIENT AND A PROCESS FOR PRODUCING THE QUINAZOLINE DERIVATIVES | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1983-09-07 | — | — | EP | disclosed |
| EP-0028031-A1 | Novel quinazoline derivatives, a pharmaceutical composition containing such derivatives as active ingredient and a process for producing the quinazoline derivatives | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | CNR2, GRIN2C, GRIN2B | MAPT 1504/4885SMN1; SMN2 674/4885BLM 4131/4885 |
| US-20170022250-A1 | TRIPEPTIDE EPOXYKETONE COMPOUND CONSTRUCTED BY HETEROCYCLE AND PREPARATION METHOD AND USE THEREOF | VIP, DNPEP, PREP | MAPT 4792/4885SMN1; SMN2 4538/4885BLM 2674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.