Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 3/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110552 | 0.90 | TSHR (0.78) | TSHRBTN3A1SRCFNTAFNTB | |
| SCHEMBL8933666 | 0.83 | TSHR (0.84) | TSHRBTN3A1SRCCETPPDPK1 | |
| SCHEMBL27908642 | 0.79 | TSHR (1.00) | TSHRSRCCETPPDPK1MTOR | |
| SCHEMBL51316 | 0.79 | TSHR (1.00) | TSHRSRCCETPPDPK1MTOR | |
| SCHEMBL6749263 | 0.78 | TSHR (0.75) | TSHRBTN3A1SRCFNTAFNTB | |
| SCHEMBL4338628 | 0.78 | TSHR (0.62) | TSHRBTN3A1SRCFNTAFNTB | |
| Hydrochloric Acid SCHEMBL10722992 | 0.77 | TSHR (0.96) | TSHRSRCCETPPDPK1MTOR | |
| SCHEMBL4219700 | 0.77 | TSHR (0.96) | TSHRSRCCETPPDPK1MTOR | |
| Ammonia Solution, Strong SCHEMBL7268743 | 0.77 | TSHR (0.96) | TSHRSRCCETPPDPK1MTOR | |
| SCHEMBL9446520 | 0.77 | TSHR (0.96) | TSHRSRCCETPPDPK1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070210476-A1 | Machinable Resin Molded Product, Material For Forming The Same, And Model Made Of The Same | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| EP-1728832-A1 | MOLDING OF RESIN FOR CUTTING OPERATION, MATERIAL FOR FORMATION THEREOF AND MODEL | Sanyo Chemical Industries, Ltd. (JP) | 2006-12-06 | — | — | EP | disclosed |