Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
| ▸ | GABRE | P78334 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL5463412 | 1.00 | TDP1 (0.53) | TDP1LMNAALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL4437928 | 1.00 | TDP1 (0.53) | TDP1LMNAALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL29701282 | 1.00 | TDP1 (0.53) | TDP1LMNAALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL31414030 | 1.00 | TDP1 (0.53) | TDP1LMNAALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL5461534 | 1.00 | TDP1 (0.53) | TDP1LMNAALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL5461431 | 1.00 | TDP1 (0.53) | TDP1LMNAALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL23648263 | 1.00 | TDP1 (0.53) | TDP1LMNAALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL5459195 | 1.00 | TDP1 (0.53) | TDP1LMNAALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL153503 | 1.00 | TDP1 (0.53) | TDP1LMNAALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL4556689 | 0.95 | TDP1 (0.48) | TDP1LMNAALOX15HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840146-B1 | Polyurethane polymer having bisphenol group and photoimageable composition containing the same | ETERNAL MAT CO LTD (TW) | 2018-03-07 | — | — | EP | disclosed |
| US-8835522-B2 | Polyurethane polymer having bisphenol group and photoimageable composition containing the same | ETERNAL CHEMICAL CO., LTD. (TW) | 2014-09-16 | — | — | US | disclosed |
| EP-1840146-A1 | Polyurethane polymer having bisphenol group and photoimageable composition containing the same | Eternal Chemical Co., Ltd. (TW) | 2007-10-03 | — | — | EP | disclosed |
| US-20070225467-A1 | Polyurethane polymer having bisphenol group and photoimageable composition containing the same | ETERNAL MATERIALS CO., LTD. (TW) | 2007-09-27 | — | — | US | disclosed |