Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.77 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.77 |
| ▸ | HDAC4 | P56524 | 13/20 | 0.75 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.75 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.75 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.75 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.75 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.75 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.75 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.75 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.75 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
| ▸ | CFD | P00746 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037923 | 0.99 | HDAC6 (0.74) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL1067946 | 0.88 | HDAC6 (0.81) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL6037928 | 0.87 | HDAC6 (0.79) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL6037929 | 0.87 | HDAC6 (0.79) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL6386310 | 0.87 | HDAC6 (1.00) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL16016602 | 0.87 | HDAC1 (1.00) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL14135053 | 0.86 | HDAC6 (0.72) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL31203555 | 0.86 | HDAC6 (0.72) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL4837664 | 0.86 | HDAC6 (0.72) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL28608420 | 0.86 | HDAC6 (0.72) | HDAC6HDAC1HDAC4HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-20 | — | — | US | disclosed |
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | HDAC6 17/4885HDAC1 1/4885HDAC4 7/4885 |
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HAT1 | HDAC6 11/4885HDAC1 1/4885HDAC4 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.