⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9741518 | 0.95 | — | — | |
| SCHEMBL2416981 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL29142712 | 0.67 | — | — | |
| SCHEMBL23395275 | 0.62 | — | — | |
| SCHEMBL23132623 | 0.62 | — | — | |
| SCHEMBL11964384 | 0.59 | — | — | |
| SCHEMBL14505491 | 0.59 | — | — | |
| SCHEMBL1686574 | 0.59 | — | — | |
| SCHEMBL14505493 | 0.56 | — | — | |
| SCHEMBL56411 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2465541-B1 | Improved processes for making hydrazides | WYETH LLC (US) | 2018-07-18 | — | — | EP | disclosed |
| CN-108026026-A | Beta-amino acids and analog and its application as the β-substituted of chemotherapeutics | 夸德里加生物科学公司 | 2018-05-11 | — | — | CN | disclosed |
| US-9738602-B2 | Processes for making hydrazides | WYETH LLC (US) | 2017-08-22 | — | — | US | disclosed |
| EP-2155258-B1 | IMPROVED PROCESSES FOR MAKING HYDRAZIDES | WYETH LLC (US) | 2017-08-16 | — | — | EP | disclosed |
| US-20160176809-A1 | PROCESSES FOR MAKING HYDRAZIDES | WYETH LLC (US) | 2016-06-23 | — | — | US | disclosed |
| US-9227924-B2 | Processes for making hydrazides | WYETH LLC (US) | 2016-01-05 | — | — | US | disclosed |
| US-20150099865-A1 | PROCESSES FOR MAKING HYDRAZIDES | WYETH LLC (US) | 2015-04-09 | — | — | US | disclosed |
| US-8853451-B2 | Processes for making hydrazides | WYETH LLC (US) | 2014-10-07 | — | — | US | disclosed |
| US-20130211053-A1 | PROCESSES FOR MAKING HYDRAZIDES | WYETH LLC (US) | 2013-08-15 | — | — | US | disclosed |
| US-8383857-B2 | Processes for making hydrazides | WYETH LLC (US) | 2013-02-26 | — | — | US | disclosed |
| EP-2465541-A1 | Improved processes for making hydrazides | Wyeth LLC (US) | 2012-06-20 | — | — | EP | disclosed |
| US-20120130052-A1 | PROCESSES FOR MAKING HYDRAZIDES | WYETH LLC (US) | 2012-05-24 | — | — | US | disclosed |
| CN-101835494-B | Improved process for making hydrazides | WYETH LLC (US) | 2012-02-15 | — | — | CN | disclosed |
| US-8110705-B2 | Processes for making hydrazides | WYETH LLC (US) | 2012-02-07 | — | — | US | disclosed |
| EP-2155258-A1 | IMPROVED PROCESSES FOR MAKING HYDRAZIDES | Wyeth LLC (US) | 2010-02-24 | — | — | EP | disclosed |
| US-20080312422-A1 | PROCESSES FOR MAKING HYDRAZIDES | WYETH (US) | 2008-12-18 | — | — | US | disclosed |
| WO-2008147765-A1 | IMPROVED PROCESSES FOR MAKING HYDRAZIDES | WYETH (US) | 2008-12-04 | — | — | WO | disclosed |