SCHEMBL5463165

SCHEMBL5463165

O=C(O)CCCCC(=O)OC(=O)CCC(=O)OC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
MAPK1 P28482 1/20 0.40
TP53 P04637 1/20 0.40
PPARA Q07869 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
ALDH1A1 P00352 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
PDE4B Q07343 1/20 0.38
MAPT P10636 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27520538 0.97 TSHR (0.43) TSHRMAPK1TP53PPARAHDAC3
SCHEMBL3896406 0.91 TSHR (0.48) TSHRTP53ALDH1A1HTTSMN1; SMN2
SCHEMBL1134580 0.91 MAPK1 (0.46) TSHRMAPK1PPARAHDAC3HDAC4
Ethylene Glycol SCHEMBL27388410 0.90 MAPK1 (0.41) TSHRMAPK1TP53PPARAHDAC3
Terephthalic Acid SCHEMBL25193265 0.90 TSHR (0.46) TSHRMAPK1TP53PPARAHDAC3
SCHEMBL6841992 0.90 TSHR (0.46) TSHRTP53ALDH1A1HTTMAPT
SCHEMBL8379024 0.90 MAPK1 (0.49) TSHRMAPK1PPARAHDAC3HDAC4
SCHEMBL29154817 0.90 MAPK1 (0.49) TSHRMAPK1PPARAHDAC3HDAC4
SCHEMBL27951955 0.90 TSHR (0.46) TSHRTP53ALDH1A1HTTSMN1; SMN2
SCHEMBL26127917 0.90 MAPK1 (0.49) TSHRMAPK1PPARAHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120245259-A1 TERNARY MIXTURE OF BIODEGRADABLE POLYESTERS AND PRODUCTS OBTAINED THEREFROM NOVAMONT S.P.A. (IT) 2012-09-27 US disclosed
US-20070203291-A1 TERNARY MIXTURE OF BIODEGRADABLE POLYESTERS AND PRODUCTS OBTAINED THEREFROM NOVAMONT S.P.A. (IT) 2007-08-30 US disclosed
EP-1355985-B1 A TERNARY MIXTURE OF BIODEGRADABLE POLYESTERS AND PRODUCTS OBTAINED THEREFROM NOVAMONT SPA (IT) 2004-08-04 EP disclosed
US-20040092672-A1 Ternary mixture of biodegradable polyesters and products obtained therefrom NOVAMONT S.P.A. (IT) 2004-05-13 US disclosed
EP-1355985-A1 A TERNARY MIXTURE OF BIODEGRADABLE POLYESTERS AND PRODUCTS OBTAINED THEREFROM NOVAMONT S.p.A. (IT) 2003-10-29 EP disclosed
WO-2002059198-A1 A TERNARY MIXTURE OF BIODEGRADABLE POLYESTERS AND PRODUCTS OBTAINED THEREFROM NOVAMONT S.P.A. (IT) 2002-08-01 WO disclosed