⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546438 | 0.87 | — | — | |
| SCHEMBL7029470 | 0.84 | — | — | |
| SCHEMBL3239616 | 0.84 | — | — | |
| SCHEMBL3238009 | 0.84 | — | — | |
| SCHEMBL3237704 | 0.75 | — | — | |
| SCHEMBL2136 | 0.68 | — | — | |
| SCHEMBL680491 | 0.68 | — | — | |
| SCHEMBL2496 | 0.68 | — | — | |
| SCHEMBL27960 | 0.64 | — | — | |
| SCHEMBL29351 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288400-B1 | SUBSTITUTED ISOQUINOLINES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1993-02-03 | — | — | EP | claimed |
| US-4795755-A | ANTISECRETORY, ANTIULCER AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-01-03 | — | — | US | claimed |
| EP-0288400-A1 | Substituted isoquinolines | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-10-26 | — | — | EP | claimed |
| US-4775760-A | Dibenzo[f,ij]isoquinoline-2,7-dione derivatives | EASTMAN KODAK COMPANY (US) | 1988-10-04 | — | — | US | claimed |
| US-4748165-A | ANTISECRETORY AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-31 | — | — | US | claimed |
| US-4746672-A | HISTAMINE H-2 ANTAGONISTS WHICH INHIBIT GASTRIC ACID SECRETION | ICI AMERICAS INC. (US) | 1988-05-24 | — | — | US | claimed |
| US-4696933-A | INHIBIT GASTRIC ACID SECRETION | ICI AMERICAS INC. (GB) | 1987-09-29 | — | — | US | claimed |
| US-4665073-A | HISTAMINE H2-ANTAGONISTS | ICI AMERICAS INC. (GB) | 1987-05-12 | — | — | US | claimed |
| US-4657908-A | Carbonyl derivatives | ICI AMERICAS, INC. (US) | 1987-04-14 | — | — | US | claimed |
| EP-0060697-B1 | HETEROCYCLIC DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-12-30 | — | — | EP | claimed |
| US-4447441-A | ANTIHISTAMINE, ANTIULCER AND ANTISECRETORY AGENT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-08 | — | — | US | claimed |
| EP-0103390-A2 | Guanidine-containing esters as histamine H2 receptor blockers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-03-21 | — | — | EP | claimed |
| EP-0067508-A1 | Amidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-22 | — | — | EP | claimed |
| EP-0065823-A1 | Heterocyclic guanidines as histamine H-2 antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-01 | — | — | EP | claimed |
| EP-0060697-A1 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0060730-A2 | Bicyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0060696-A1 | Nitrogen heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0060094-A2 | Guanidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-15 | — | — | EP | claimed |
| EP-0060093-A2 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-15 | — | — | EP | claimed |
| EP-0059597-A2 | Guanidino-substituted heterocyclic derivatives having histamine H-2 antagonist activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-08 | — | — | EP | claimed |