Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458034 | 0.91 | DPP4 (0.69) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| Hydrochloric Acid SCHEMBL5471020 | 0.90 | DPP4 (0.68) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL5471005 | 0.90 | DPP4 (0.57) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| Hydrochloric Acid SCHEMBL5182318 | 0.87 | MAPT (0.49) | DPP4BRAFTSHRMEN1KMT2A | |
| SCHEMBL5470877 | 0.86 | DPP4 (0.55) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL5183129 | 0.84 | DPP4 (0.50) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL5463563 | 0.82 | DPP4 (0.57) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL5477279 | 0.81 | DPP4 (0.74) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL5465930 | 0.80 | DPP4 (0.54) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| Hydrochloric Acid SCHEMBL5466172 | 0.80 | BRAF (0.52) | DPP4BRAFTSHRMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236810-B2 | Substituted 8-aminoalkylthioxanthines, and their use as inhibitors of dipeptidyl peptidase IV | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2012-08-07 | — | — | US | disclosed |
| US-20070265284-A1 | SUBSTITUTED 8-AMINOALKYLTHIOXANTHINES, AND THEIR USE AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265284-A1 | SUBSTITUTED 8-AMINOALKYLTHIOXANTHINES, AND THEIR USE AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | DPP4, DPP8, DPP7 | DPP4 1/4885CHRM1 4333/4885CHRM2 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.