SCHEMBL546523

SCHEMBL546523

N#Cc1cc(Cl)ccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363423 1.00
SCHEMBL5700591 0.77
SCHEMBL6385216 0.77
SCHEMBL31133396 0.76 MYC (0.62)
SCHEMBL9792895 0.76 MYC (0.62)
SCHEMBL1145922 0.74
SCHEMBL995799 0.74 CLK4 (0.44)
SCHEMBL131627 0.74
SCHEMBL29598148 0.74 CLK4 (0.44)
SCHEMBL1094766 0.74 MYC (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 806 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116375636-A Novel method for synthesizing 4-fluoropyridine-2-carbonitrile 浙江工业大学 2023-07-04 CN claimed
CN-112250622-B Preparation method of 4-fluoropyridine-2-amine 山东省海洋化工科学研究院 2022-05-27 CN claimed
CN-112279809-A Preparation method of 2-cyano-4-fluoropyridine 山东省海洋化工科学研究院 2021-01-29 CN claimed
CN-112250622-A Preparation method of 4-fluoropyridine-2-amine 山东省海洋化工科学研究院 2021-01-22 CN claimed
CN-103664768-A Compound 2-(cyclopropylamino)-3-carboxylic acid-4-chloropyridine and application thereof QINGDAO WENCHUANG TECH CO LTD 2014-03-26 CN claimed
WO-2026101698-A1 HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF PROTAGONIST THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
US-12624051-B2 Macrocyclic compounds, compositions, and methods of using thereof GENZYME CORPORATION (US) 2026-05-12 US disclosed
US-12617774-B2 Substituted indole compounds and methods of use thereof NOVARTIS AG (CH) 2026-05-05 US disclosed
EP-4142732-B1 METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS GLOBAL BLOOD THERAPEUTICS INC (US) 2026-04-22 EP disclosed
EP-3565808-B1 COMPOUNDS USEFUL FOR TREATING GASTROINTESTINAL TRACT DISORDERS ARDELYX INC (US) 2026-03-04 EP disclosed
US-12559502-B2 Thieno pyrimidines as ferroportin inhibitors Global Blood Therapeutics, Inc (US) 2026-02-24 US disclosed
US-20260008786-A1 MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF SCHRODINGER, LLC 2026-01-08 US disclosed
US-4170654-A Antihypertensive compositions containing N-heterocyclicalanines and α- MERCK & CO., INC. (US) 1979-10-09 US disclosed
US-4160835-A Antihypertensive compositions containing an arylsubstituted alanine and a phenyl hydrazinopropionic acid MERCK & CO., INC. (US) 1979-07-10 US disclosed
US-4112100-A INCREASING THE ENDOGENOUS PRODUCTION OF PROSTAGLANDINS THE UPJOHN COMPANY (US) 1978-09-05 US disclosed
US-4088766-A PRODUCTION OF PROSTAGLANDINS IN MAMMALS THE UPJOHN COMPANY (US) 1978-05-09 US disclosed
US-4008326-A INCREASING PRODUCTION OF PROSTAGLANDINS THE UPJOHN COMPANY (US) 1977-02-15 US disclosed
US-4001256-A PROSTAGLANDIN PRODUCTION IN MAMMALS THE UPJOHN COMPANY (US) 1977-01-04 US disclosed
US-3932641-A THIOACETAMIDES SMITHKLINE CORPORATION (US) 1976-01-13 US disclosed
US-3931162-A N-Aminomethyl heterocyclic thioacetamides SMITHKLINE CORPORATION (US) 1976-01-06 US disclosed