Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ULK1 | O75385 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3195244 | 1.00 | HPGD (0.66) | HPGDULK1MEN1GAAMAPT | |
| SCHEMBL3195252 | 1.00 | HPGD (0.66) | HPGDULK1MEN1GAAMAPT | |
| SCHEMBL2184247 | 0.85 | HPGD (0.89) | HPGDMEN1GAAMAPTGFER | |
| SCHEMBL12798824 | 0.82 | MEN1 (0.56) | HPGDULK1MEN1GAAMAPT | |
| SCHEMBL4668488 | 0.81 | HPGD (0.96) | HPGDMEN1GAAMAPTGFER | |
| SCHEMBL22145564 | 0.81 | HPGD (0.66) | HPGDMEN1GAAMAPTGFER | |
| SCHEMBL3211109 | 0.80 | GAA (0.72) | HPGDMEN1GAAMAPTGFER | |
| SCHEMBL3211102 | 0.80 | GAA (0.72) | HPGDMEN1GAAMAPTGFER | |
| SCHEMBL3209090 | 0.80 | HPGD (0.64) | HPGDMEN1GAAMAPTGFER | |
| SCHEMBL3209082 | 0.80 | HPGD (0.64) | HPGDMEN1GAAMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135387-A1 | Inhibitors of protein kinases | ABBOTT LABORATORIES | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135387-A1 | Inhibitors of protein kinases | MAP3K20, PACSIN2, MAP4K2 | HPGD 1820/4885ULK1 377/4885MEN1 2272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.