Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.50 |
| ▸ | PPARA | Q07869 | 18/20 | 0.50 |
| ▸ | PPARG | P37231 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5427445 | 0.87 | PPARD (0.57) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL5469620 | 0.86 | PPARD (0.54) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL5469612 | 0.86 | PPARD (0.52) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL4806979 | 0.85 | PPARD (0.55) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL4806449 | 0.85 | PPARD (0.55) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL4891955 | 0.84 | PPARD (0.62) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL4809738 | 0.84 | PPARD (0.55) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL4807795 | 0.84 | PPARD (0.51) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL4812301 | 0.84 | PPARD (0.51) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL4815055 | 0.83 | PPARD (0.50) | PPARDPPARAPPARGMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229998-B2 | Thiazole and oxazole derivatives as activators of human peroxisome proliferator activated receptors | SMITHKLINE BEECHAM CORPORATION (US) | 2007-06-12 | — | — | US | disclosed |