⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5739887 | 0.87 | — | — | |
| SCHEMBL5467718 | 0.85 | — | — | |
| SCHEMBL5469871 | 0.85 | — | — | |
| SCHEMBL5467685 | 0.83 | ADORA2A (0.62) | — | |
| SCHEMBL5468021 | 0.83 | — | — | |
| SCHEMBL5468166 | 0.82 | — | — | |
| SCHEMBL5463347 | 0.82 | — | — | |
| SCHEMBL5479791 | 0.82 | — | — | |
| SCHEMBL3188148 | 0.82 | — | — | |
| SCHEMBL5467828 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010520-A1 | Triazolopyrazines and methods of making and using the same | BIOGEN IDEC MA INC. | 2007-01-11 | — | — | US | claimed |
| EP-1615931-A1 | TRIAZOLOPYRAZINES AND METHODS OF MAKING AND USING THE SAME | Biogen Idec MA Inc. (US) | 2006-01-18 | — | — | EP | claimed |
| WO-2004092177-A1 | TRIAZOLOPYRAZINES AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC MA INC. (US) | 2004-10-28 | — | — | WO | claimed |