Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 13/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5152641 | 0.90 | PTGER1 (0.75) | PTGER1TBXA2RPPARGPTGER3CYP1A2 | |
| SCHEMBL5466740 | 0.90 | PTGER1 (0.76) | PTGER1TBXA2RPPARGPTGER3CYP1A2 | |
| SCHEMBL5480365 | 0.89 | PTGER1 (0.77) | PTGER1TBXA2RPPARGPTGER3CYP1A2 | |
| SCHEMBL14413204 | 0.88 | PTGER1 (0.71) | PTGER1TBXA2RPPARGPTGER3MRGPRX4 | |
| SCHEMBL14413133 | 0.87 | PTGER1 (0.65) | PTGER1TBXA2RPPARGPTGER3CYP1A2 | |
| SCHEMBL5480346 | 0.87 | PTGER1 (0.65) | PTGER1TBXA2RPPARGPTGER3CYP1A2 | |
| SCHEMBL5473784 | 0.87 | PTGER1 (0.82) | PTGER1TBXA2RPPARGPTGER3 | |
| SCHEMBL5476902 | 0.86 | PTGER1 (0.63) | PTGER1TBXA2RPPARGPTGER3CYP1A2 | |
| SCHEMBL5483108 | 0.85 | PTGER1 (0.60) | PTGER1TBXA2RPPARGPTGER3CYP1A2 | |
| SCHEMBL5096279 | 0.85 | PTGER1 (0.78) | PTGER1TBXA2RPPARGPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225340-A1 | Phenyl Compounds And Their Use In The Treatment Of Conditions Mediated By The Action Of Pge2 At The Ep1 Receptor | GLAXO GROUP LIMITED (GB) | 2007-09-27 | — | — | US | disclosed |
| US-20070225340-A1 | Phenyl Compounds And Their Use In The Treatment Of Conditions Mediated By The Action Of Pge2 At The Ep1 Receptor | GLAXO GROUP LIMITED (GB) | 2007-09-27 | — | — | US | disclosed |
| US-20070225340-A1 | Phenyl Compounds And Their Use In The Treatment Of Conditions Mediated By The Action Of Pge2 At The Ep1 Receptor | GLAXO GROUP LIMITED (GB) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225340-A1 | Phenyl Compounds And Their Use In The Treatment Of Conditions Mediated By The Action Of Pge2 At The Ep1 Receptor | PTGER1, PTGER2, PTGDR | PTGER1 1/4885TBXA2R 11/4885PPARG 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.