Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.61 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.57 |
| ▸ | MME | P08473 | 6/20 | 0.56 |
| ▸ | ACE | P12821 | 6/20 | 0.56 |
| ▸ | CPA1 | P15085 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287829 | 1.00 | FOLH1 (0.61) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL547122 | 1.00 | FOLH1 (0.61) | FOLH1NAALAD2MMEACECPA1 | |
| Hydrochloric Acid SCHEMBL28885042 | 0.98 | FOLH1 (0.60) | FOLH1NAALAD2MMEACECPA1 | |
| Hydrochloric Acid SCHEMBL7310747 | 0.98 | FOLH1 (0.60) | FOLH1NAALAD2MMEACECPA1 | |
| Hydrochloric Acid SCHEMBL7310754 | 0.98 | FOLH1 (0.60) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL6443921 | 0.87 | FOLH1 (0.55) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL6443925 | 0.87 | FOLH1 (0.55) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL25764848 | 0.86 | TDP1 (0.52) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL25764849 | 0.86 | TDP1 (0.52) | FOLH1NAALAD2MMEACECPA1 | |
| SCHEMBL15095619 | 0.86 | ESR1 (0.53) | FOLH1NAALAD2MMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508611-B1 | Process for production of triprenyl phenol compounds | TMS CO LTD (JP) | 2019-05-08 | — | — | EP | claimed |
| EP-2508611-B1 | Process for production of triprenyl phenol compounds | TMS CO LTD (JP) | 2019-05-08 | — | — | EP | disclosed |
| EP-2604697-B1 | Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer | UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) | 2015-07-01 | — | — | EP | disclosed |
| US-8883462-B2 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| EP-2000540-B1 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) | 2014-05-14 | — | — | EP | disclosed |
| EP-2604697-A1 | Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer | Tokyo University of Agriculture and Technology TLO (JP) | 2013-06-19 | — | — | EP | disclosed |
| EP-2508611-A1 | Process for production of triprenyl phenol compounds | Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) | 2012-10-10 | — | — | EP | disclosed |
| US-20120100579-A1 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | TOKYO UNIVERSITY OF AGRICLATURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-8110596-B2 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20090216028-A1 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2009-08-27 | — | — | US | disclosed |
| EP-2000540-A9 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) | 2009-03-25 | — | — | EP | disclosed |
| EP-2000540-A2 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) | 2008-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090216028-A1 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | PLAT, F2R, F12 | FOLH1 585/4885NAALAD2 1047/4885MME 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.