SCHEMBL5471214

SCHEMBL5471214

c1ccc2c(c1)c1ccccc1c1c2c2c3ccccc3c3cccc4c5cccc6c7ccccc7c1c(c65)c2c34

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 8/20 0.58
ALDH1A1 P00352 6/20 0.58
HSD17B10 Q99714 6/20 0.58
HPGD P15428 5/20 0.58
THRB P10828 2/20 0.58
HPRT1 P00492 1/20 0.40
TSHR P16473 5/20 0.39
MAPK1 P28482 2/20 0.39
CASP1 P29466 2/20 0.39
ERBB2 P04626 1/20 0.39
FYN P06241 1/20 0.39
MAOA P21397 1/20 0.39
ACHE P22303 1/20 0.39
AHR P35869 1/20 0.39
HIF1A Q16665 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP2A6 P11509 6/20 0.37
TDP1 Q9NUW8 3/20 0.37
CYP3A4 P08684 2/20 0.35
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5478700 1.00 CYP1A2 (0.58) CYP1A2ALDH1A1HSD17B10HPGDTHRB
SCHEMBL1978995 1.00 CYP1A2 (0.58) CYP1A2ALDH1A1HSD17B10HPGDTHRB
SCHEMBL2537906 0.97 CYP1A2 (0.55) CYP1A2ALDH1A1HSD17B10HPGDTHRB
SCHEMBL5471846 0.93 HSD17B10 (0.50) CYP1A2ALDH1A1HSD17B10HPGDTHRB
SCHEMBL5471145 0.93 CYP1A2 (0.58) CYP1A2ALDH1A1HSD17B10HPGDTHRB
SCHEMBL5476671 0.93 HSD17B10 (0.50) CYP1A2ALDH1A1HSD17B10HPGDTHRB
SCHEMBL2533864 0.93 CYP1A2 (0.58) CYP1A2ALDH1A1HSD17B10HPGDTHRB
SCHEMBL4845687 0.93 CYP1A2 (0.58) CYP1A2ALDH1A1HSD17B10HPGDTHRB
SCHEMBL11302617 0.93 CYP1A2 (0.58) CYP1A2ALDH1A1HSD17B10HPGDTHRB
SCHEMBL2538508 0.93 CYP1A2 (0.65) CYP1A2ALDH1A1HSD17B10HPGDTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-7175922-B2 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY (US) 2007-02-13 US disclosed
US-20050106415-A1 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2005-05-19 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed