SCHEMBL547137

SCHEMBL547137

O=C(OCCOC(=O)c1ccc(C(=O)OCCOC(=O)c2ccccc2)cc1)c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.79
LMNA P02545 3/20 0.73
ESR1 P03372 1/20 0.67
ESR2 Q92731 1/20 0.67
NPC1 O15118 3/20 0.65
RAB9A P51151 3/20 0.65
MAPK1 P28482 1/20 0.63
HIF1A Q16665 1/20 0.63
SLC6A2 P23975 1/20 0.63
SLC6A3 Q01959 1/20 0.63
KMT2A Q03164 1/20 0.63
ALDH1A1 P00352 2/20 0.61
F2 P00734 1/20 0.58
KDM4E B2RXH2 1/20 0.58
GAA P10253 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
TSHR P16473 2/20 0.57
HPGD P15428 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13292516 1.00 TDP1 (0.79) TDP1LMNAESR1ESR2NPC1
SCHEMBL16217656 1.00 TDP1 (0.79) TDP1LMNAESR1ESR2NPC1
SCHEMBL137486 0.98 TDP1 (0.83) TDP1LMNAESR1ESR2NPC1
SCHEMBL28286830 0.95 TDP1 (0.79) TDP1LMNAESR1ESR2NPC1
SCHEMBL11239419 0.94 TDP1 (0.70) TDP1LMNAESR1ESR2NPC1
SCHEMBL27853082 0.94 TDP1 (0.70) TDP1LMNAESR1ESR2NPC1
Ethylene SCHEMBL8622525 0.93 TDP1 (0.76) TDP1LMNAESR1ESR2NPC1
Ethylene SCHEMBL11578922 0.93 TDP1 (0.76) TDP1LMNAESR1ESR2NPC1
Ethylene SCHEMBL9928862 0.93 TDP1 (0.76) TDP1LMNAESR1ESR2NPC1
Ethylene SCHEMBL7587624 0.93 TDP1 (0.76) TDP1LMNAESR1ESR2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1137761-B1 CUTINASE VARIANTS NOVOZYMES AS (DK) 2007-08-01 EP claimed
US-6960459-B2 Fungal cutinase for use in the processing of textiles NOVOZYMES A/S (DK) 2005-11-01 US claimed
EP-1290150-A1 CUTINASE VARIANTS Novozymes A/S (DK) 2003-03-12 EP claimed
US-20020123123-A1 Fungal cutinase for use in the processing of textiles NOVOZYMES A/S (DK) 2002-09-05 US claimed
WO-2001092502-A1 CUTINASE VARIANTS NOVOZYMES A/S (DE) 2001-12-06 WO claimed
EP-1137761-A1 CUTINASE VARIANTS Novozymes A/S (DK) 2001-10-04 EP claimed
WO-2000034450-A1 CUTINASE VARIANTS NOVOZYMES A/S (DK) 2000-06-15 WO claimed
WO-2025081024-A2 SYSTEMS, METHODS, AND COMPOSITIONS RELATED TO COPOLYMERIZATION OF CRYSTALLIZABLE POLYMERS FOR ENZYMATIC DEGRADATION Protein Evolution Inc. (US) 2025-04-17 WO disclosed
US-20240352064-A1 METHODS AND COMPOSITIONS FOR THE SEPARATION OF PARTICLES FROM A FLUID Protein Evolution Inc. (US) 2024-10-24 US disclosed
WO-2024197030-A2 METHODS AND COMPOSITIONS FOR THE SEPARATION OF PARTICLES FROM A FLUID Protein Evolution Inc. (US) 2024-09-26 WO disclosed
US-20240286178-A1 SYSTEMS AND METHODS FOR ENZYMATIC DEGRADATION OF POLYMERS, INCLUDING COPOLYMERS, WITH A VARIETY OF ENZYMES PROTEIN EVOLUTION INC (US) 2024-08-29 US disclosed
US-20240228728-A1 SYSTEMS AND METHODS FOR ENZYMATIC DEGRADATION OF POLYMERS, INCLUDING COPOLYMERS, OF ADVANTAGOUS PARTICLE SIZE Protein Evolution Inc. (US) 2024-07-11 US disclosed
US-20240228727-A1 SYSTEMS AND METHODS FOR PRETREATMENT AND/OR ENZYMATIC DEGRADATION OF CRYSTALLIZABLE POLYMERS, INCLUDING COPOLYMERS Protein Evolution Inc. (US) 2024-07-11 US disclosed
EP-1290150-B1 CUTINASE VARIANTS NOVOZYMES AS (DK) 2005-08-24 EP disclosed
US-6815190-B1 HAVING IMPROVED THERMOSTABILITY; USED IN THE ENZYMATIC HYDROLYSIS OF CYCLIC OLIGOMERS OF POLY(ETHYLENE TEREPHTHALATE) IN THE FINISHING OF YARN OR FABRIC FROM FIBERS NOVOZYMES A/S (DK) 2004-11-09 US disclosed
EP-1290150-A1 CUTINASE VARIANTS Novozymes A/S (DK) 2003-03-12 EP disclosed
US-20020123123-A1 Fungal cutinase for use in the processing of textiles NOVOZYMES A/S (DK) 2002-09-05 US disclosed
WO-2001092502-A1 CUTINASE VARIANTS NOVOZYMES A/S (DE) 2001-12-06 WO disclosed
EP-1137761-A1 CUTINASE VARIANTS Novozymes A/S (DK) 2001-10-04 EP disclosed
WO-2000034450-A1 CUTINASE VARIANTS NOVOZYMES A/S (DK) 2000-06-15 WO disclosed