SCHEMBL5477374

SCHEMBL5477374

CCCCCCCCCCc1c(O)cc(C(=O)c2ccccc2)c(O)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 4/20 0.48
PPARA Q07869 2/20 0.48
MCL1 Q07820 5/20 0.46
BCL2 P10415 2/20 0.46
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
RECQL P46063 1/20 0.43
HSD17B10 Q99714 1/20 0.43
STAT3 P40763 1/20 0.42
BID P55957 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAK1 Q16611 2/20 0.42
PPARG P37231 1/20 0.42
EP300 Q09472 1/20 0.42
KAT2A Q92830 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5480015 1.00 KAT8 (0.48) KAT8PPARAMCL1BCL2CES2
SCHEMBL27607231 1.00 KAT8 (0.48) KAT8PPARAMCL1BCL2CES2
SCHEMBL11790314 0.89 MCL1 (0.47) KAT8PPARAMCL1BCL2CES2
SCHEMBL11790237 0.89 MCL1 (0.47) KAT8PPARAMCL1BCL2CES2
SCHEMBL28132998 0.84 BCL2 (0.54) MCL1BCL2KDM4ELMNACYP3A4
SCHEMBL27621974 0.83 BCL2 (0.49) MCL1BCL2CES2CES1KDM4E
SCHEMBL28758148 0.81 KAT8 (0.50) KAT8PPARAMCL1CES2CES1
SCHEMBL27444636 0.81 KAT8 (0.50) KAT8PPARAMCL1CES2CES1
SCHEMBL2868258 0.80 HPGD (0.47) PPARAMCL1BCL2KDM4ELMNA
SCHEMBL1979931 0.80 KAT8 (0.72) KAT8PPARAMAPTSTAT3PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070141355-A1 Plastic lens and process for preparing the lens HOYA CORPORATION 2007-06-21 US disclosed