Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.67 |
| ▸ | RET | P07949 | 1/20 | 0.63 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.59 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.58 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.57 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.56 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.56 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.56 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.56 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.56 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | TDO2 | P48775 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477578 | 1.00 | MEN1 (0.76) | MEN1KMT2ALRRK2RETPDGFRB | |
| SCHEMBL13595188 | 0.89 | MEN1 (0.64) | MEN1KMT2ALRRK2RETMDM2 | |
| SCHEMBL5469641 | 0.86 | LRRK2 (0.70) | MEN1KMT2ALRRK2RETPDGFRB | |
| SCHEMBL5469637 | 0.86 | LRRK2 (0.70) | MEN1KMT2ALRRK2RETPDGFRB | |
| SCHEMBL17179651 | 0.86 | MEN1 (1.00) | MEN1KMT2ALRRK2RETPDGFRB | |
| SCHEMBL14675111 | 0.84 | MEN1 (1.00) | MEN1KMT2AMDM2RPS6KA3FLT3 | |
| SCHEMBL14674713 | 0.84 | NPC1 (0.70) | MEN1KMT2ALRRK2RETPDGFRB | |
| SCHEMBL5472890 | 0.84 | PLK4 (0.70) | MEN1KMT2ALRRK2RETPDGFRB | |
| SCHEMBL14674712 | 0.84 | NPC1 (0.70) | MEN1KMT2ALRRK2RETPDGFRB | |
| SCHEMBL14675110 | 0.84 | MEN1 (1.00) | MEN1KMT2AMDM2RPS6KA3FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167488-A1 | Novel therapeutic use | LEO PHARMA A/S (DK) | 2007-07-19 | — | — | US | claimed |
| US-20070167488-A1 | Novel therapeutic use | LEO PHARMA A/S (DK) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167488-A1 | Novel therapeutic use | MAG, PMP22, MYT1 | MEN1 1603/4885KMT2A 1891/4885LRRK2 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.