Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 19/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5399884 | 1.00 | KCNH2 (0.69) | KCNH2 | |
| SCHEMBL5718398 | 0.88 | KCNH2 (0.67) | KCNH2 | |
| SCHEMBL5417258 | 0.88 | KCNH2 (0.67) | KCNH2 | |
| SCHEMBL5399893 | 0.82 | KCNH2 (0.67) | KCNH2 | |
| SCHEMBL5024658 | 0.82 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL5634038 | 0.82 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL5399889 | 0.82 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL5477886 | 0.82 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL5017472 | 0.76 | KCNH2 (0.77) | KCNH2 | |
| SCHEMBL5076795 | 0.76 | KCNH2 (1.00) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007518742-A | — | — | 2007-07-12 | — | — | JP | claimed |
| EP-1718633-A1 | N-TYPE CALCIUM CHANNEL BLOCKERS | Neuromed Pharmaceuticals, Ltd. (CA) | 2006-11-08 | — | — | EP | claimed |
| WO-2005070919-A1 | N-TYPE CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2005-08-04 | — | — | WO | claimed |
| EP-1718633-A1 | N-TYPE CALCIUM CHANNEL BLOCKERS | Neuromed Pharmaceuticals, Ltd. (CA) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005070919-A1 | N-TYPE CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2005-08-04 | — | — | WO | disclosed |