Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664897 | 0.80 | KDM4E (0.51) | KCNH2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL28339210 | 0.80 | TYR (0.40) | GPR35SRCESR1ADRA2AADORA3 | |
| SCHEMBL5414444 | 0.79 | SRC (0.40) | SRCESR1ADRA2AADORA3TACR2 | |
| SCHEMBL250349 | 0.78 | KDM4E (0.50) | KCNH2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL30127786 | 0.78 | KDM4E (0.50) | KCNH2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL10126309 | 0.78 | KDM4E (0.46) | KCNH2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL27889507 | 0.78 | KDM4E (0.46) | KCNH2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL27889589 | 0.78 | KDM4E (0.46) | KCNH2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL19767756 | 0.76 | SRC (0.38) | SRCESR1ADRA2AADORA3TACR2 | |
| SCHEMBL6406696 | 0.75 | KDM4E (0.45) | KCNH2KDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287821-A1 | Synthesis of Polynaphthalenes and Their Use | BASF AKTIENGESELLSCHAFT (DE) | 2007-12-13 | — | — | US | disclosed |