⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5240 | 0.93 | — | — | |
| SCHEMBL5275 | 0.90 | — | — | |
| SCHEMBL21114244 | 0.90 | — | — | |
| SCHEMBL21114337 | 0.90 | — | — | |
| SCHEMBL5142 | 0.90 | — | — | |
| SCHEMBL21114246 | 0.90 | — | — | |
| SCHEMBL4324 | 0.90 | — | — | |
| SCHEMBL21114314 | 0.90 | — | — | |
| SCHEMBL5171 | 0.85 | — | — | |
| SCHEMBL3817498 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115305096-B | Negative dielectric anisotropic liquid crystal composition and liquid crystal display device | 烟台显华科技集团股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-115287083-B | Negative dielectric anisotropic liquid crystal composition and liquid crystal display device | 烟台显华科技集团股份有限公司 | 2024-03-01 | — | — | CN | disclosed |
| US-11840528-B2 | Isoxazolyl ether derivatives as GABAA α5 PAM | HOFFMANN-LA ROCHE INC. (US) | 2023-12-12 | — | — | US | disclosed |
| CN-115305096-A | Negative dielectric anisotropy liquid crystal composition and liquid crystal display device | 烟台显华科技集团股份有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-115287083-A | Negative dielectric anisotropy liquid crystal composition and liquid crystal display device | 烟台显华科技集团股份有限公司 | 2022-11-04 | — | — | CN | disclosed |
| EP-3807269-A1 | NEW ISOXAZOLYL ETHER DERIVATIVES AS GABA A ALPHA5 PAM | F. Hoffmann-La Roche AG (CH) | 2021-04-21 | — | — | EP | disclosed |
| US-20210094945-A1 | NEW ISOXAZOLYL ETHER DERIVATIVES AS GABA A ALPHA5 PAM | HOFFMANN-LA ROCHE INC. (US) | 2021-04-01 | — | — | US | disclosed |
| CN-112424196-A | Novel isoxazolyl ether derivatives as GABAA alpha 5 PAM | 豪夫迈·罗氏有限公司 | 2021-02-26 | — | — | CN | disclosed |
| EP-2785695-B1 | NEW BICYCLIC DIHYDROISOQUINOLINE-1-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2020-06-17 | — | — | EP | disclosed |
| EP-3653618-A1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2020-05-20 | — | — | EP | disclosed |
| US-20100056640-A1 | AMIDE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2151431-A1 | AMIDE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2010-02-10 | — | — | EP | disclosed |
| EP-2143709-A1 | AMIDE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2010-01-13 | — | — | EP | disclosed |
| CN-100335466-C | Pyrimidine compounds and their use as pesticides | SUMITOMO CHEMICAL CO (JP) | 2007-09-05 | — | — | CN | disclosed |
| US-7223769-B2 | Pyrimidine compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-29 | — | — | US | disclosed |
| EP-1483249-B1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2006-09-06 | — | — | EP | disclosed |
| US-20050171130-A1 | Pyrimidine compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-08-04 | — | — | US | disclosed |
| CN-1639131-A | Pyrimidine compounds and their use as pesticides | SUMITOMO CHEMICAL CO (JP) | 2005-07-13 | — | — | CN | disclosed |
| EP-1483249-A1 | PYRIMIDINE COMPOUNDS AND THEIR USE AS PESTICIDES | Sumitomo Chemical Company, Limited (JP) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003076415-A1 | PYRIMIDINE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-18 | — | — | WO | disclosed |