⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217398 | 0.72 | — | — | |
| SCHEMBL5951131 | 0.67 | — | — | |
| SCHEMBL9828715 | 0.65 | — | — | |
| SCHEMBL2890343 | 0.61 | — | — | |
| SCHEMBL3852652 | 0.61 | — | — | |
| SCHEMBL104270 | 0.61 | — | — | |
| SCHEMBL5916128 | 0.61 | — | — | |
| SCHEMBL9852397 | 0.60 | — | — | |
| SCHEMBL9263272 | 0.60 | — | — | |
| SCHEMBL3019375 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668176-B1 | A NOVEL PROCESS FOR SYNTHESIS OF POLYPHENOLS | SPHAERA PHARMA PTE LTD (SG) | 2017-05-17 | — | — | EP | claimed |
| US-9428482-B2 | Process for synthesis of polyphenols | SPHAERA PHARMA PTE. LTD. (SG) | 2016-08-30 | — | — | US | claimed |
| US-20140031421-A1 | NOVEL PROCESS FOR SYNTHESIS OF POLYPHENOLS | SPHAERA PHARMA PTE. LTD. (SG) | 2014-01-30 | — | — | US | claimed |
| US-8410305-B2 | Intermediates and methods for the preparation of epothilones | KOSAN BIOSCIENCES INCORPORATED (US) | 2013-04-02 | — | — | US | claimed |
| US-20100267943-A1 | INTERMEDIATES AND METHODS FOR THE PREPARATION OF EPOTHILONES | KOSAN BIOSCIENCES INCORPORATED | 2010-10-21 | — | — | US | claimed |
| WO-2009064800-A1 | INTERMEDIATES AND METHODS FOR THE PREPARATION OF EPOTHILONES | KOSAN BIOSCIENCES, INC. (US) | 2009-05-22 | — | — | WO | claimed |
| US-20080262070-A1 | Pharmaceutically Active Tetrahydro-Pyrrolizinone Compounds | BAUMANN KARL | 2008-10-23 | — | — | US | claimed |
| EP-1937685-A1 | TETRAHYDRO-PYRROLIZINONE COMPOUNDS AS LFA-I MEDIATORS | Novartis AG (CH) | 2008-07-02 | — | — | EP | claimed |
| WO-2007039286-A1 | TETRAHYDRO-PYRROLIZINONE COMPOUNDS AS LFA-I MEDIATORS | NOVARTIS AG (CH) | 2007-04-12 | — | — | WO | claimed |
| US-6054582-A | Process for pyrimidinone compounds | ROHM AND HAAS COMPANY (US) | 2000-04-25 | — | — | US | claimed |
| CN-1162598-A | Improved process for pyrimidinone compounds | UNIV PRINCETON (US) | 1997-10-22 | — | — | CN | claimed |
| US-5629264-A | 2-aryl-5,6-dihydropyrimidinones and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1997-05-13 | — | — | US | claimed |
| EP-0579424-B1 | 2-substituted pyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1996-10-23 | — | — | EP | claimed |
| EP-0733622-A1 | 2-Aryl-5,6-dihydropyrimidinones and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1996-09-25 | — | — | EP | claimed |
| EP-0696588-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1996-02-14 | — | — | EP | claimed |
| EP-0663396-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-07-19 | — | — | EP | claimed |
| US-5380852-A | Plant safening agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | claimed |
| US-5300477-A | 2-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-04-05 | — | — | US | claimed |
| US-5294737-A | Hydrolysis, cyclization, condensation | THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) | 1994-03-15 | — | — | US | claimed |
| EP-0579424-A1 | 2-substituted pyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-01-19 | — | — | EP | claimed |