SCHEMBL5481222

SCHEMBL5481222

CCOC(=O)C(C)(C)Oc1c(C)cc(CN(Cc2ncc(C)o2)Cc2nc(-c3ccc(C)s3)oc2C)cc1C

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARG P37231 15/20 0.47
PPARA Q07869 14/20 0.47
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
HTR2A P28223 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5479507 0.92 PPARG (0.56) PPARGPPARAALDH1A1KDM4EMEN1
SCHEMBL5472016 0.89 PPARG (0.51) PPARGPPARAALDH1A1KDM4EMEN1
SCHEMBL5481565 0.88 PPARG (0.47) PPARGPPARAALDH1A1KDM4EMEN1
SCHEMBL5483091 0.86 PPARG (0.47) PPARGPPARAALDH1A1KDM4EMEN1
SCHEMBL5479549 0.81 PPARG (0.60) PPARGPPARAALDH1A1KDM4EMEN1
SCHEMBL5485664 0.79 PPARA (0.71) PPARGPPARAKDM4E
SCHEMBL5480338 0.79 PPARG (0.56) PPARGPPARAALDH1A1KDM4EMEN1
SCHEMBL5484176 0.78 PPARA (0.44) PPARGPPARA
SCHEMBL5478122 0.77 PPARG (0.66) PPARGPPARA
SCHEMBL5477846 0.76 PPARA (0.54) PPARGPPARAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same PPARA, PPARG, PPARD PPARG 2/4885PPARA 1/4885ALDH1A1 620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.